5 Years review of periocular basal cell carcinoma and proposed follow-up protocol

Abstract

In all, 67% were nodular BCC and 45.4% located in the lower eyelid. The main outcome measure was the recurrence rate. None of the patients with primary nodular BCC suffered recurrence. The recurrence rate for primary morphoeaform BCC following complete excision is 3.8%. In total, 8.1% of patients had several lesions simultaneously whereas 7.8% patients had BCC in multiple locations subsequently (metachronous). Three patients who had previously recurrent BCC (rBCC) treated elsewhere or not using this method had orbital/lacrimal drainage system involvement requiring exenteration. Conclusion We recommend that patients with a single, completely excised primary solid or nodular BCC can be discharged after one 6-monthly review, although they should be instructed to monitor for the development of further lesions. The incidence of recurrence for primary morphoeaform BCC is 3.8% and for rBCC is 3.6% over 5 years and these patients should stay under review for this period.

Histological subtypes of periocular basal cell carcinoma

“…Additionally, latitude has been shown to influence BCC subtype more than body site, with significantly higher proportions of infiltrative and superficial BCC found on the head and neck in the Townsville study compared with in the periocular region in the United Kingdom study. 7,11 Our findings are in keeping with this, as we reported higher proportions of infiltrative and superficial BCC compared with studies of head and neck BCC conducted at higher latitudes.…”

“…Our study demonstrated higher rates of infiltrative BCC compared with superficial subtype, consistent with previous reports from Townsville, Brisbane and the United Kingdom of facial and periocular BCC. 7,11,12 These findings may be attributable to the theory which suggests that superficial BCC results from acute, intense sun exposure to skin that is less exposed to sunlight and thus less tanned.…”

“…15 In general, infiltrative and superficial subtypes have been shown to occur more frequently in the periocular region and at lower latitudes compared with on the head and neck and at higher latitudes. [6][7][8]11,12 Thus, these subtypes may be associated with greater sun exposure which occurs at lower latitudes. Additionally, latitude has been shown to influence BCC subtype more than body site, with significantly higher proportions of infiltrative and superficial BCC found on the head and neck in the Townsville study compared with in the periocular region in the United Kingdom study.…”

“…Few studies have examined the proportion of periocular BCC subtypes. 11,12 To aid in the management of periocular BCC, we aimed to investigate the proportion of BCC subtypes occurring in the periocular region.…”

Characteristics of Malignant Eyelid Basal Cell Carcinoma in Cicendo Eye Hospital Bandung from 2013 to 2015

“…This finding is particularly constant with previous study in Oradea while interestingly, most other studies describing nodular BCC as the most common histological type. 2,6,9,11 There are limitations in this study where this study may not represent the entire Bandung population. Nonetheless, this study provides a compelling overview of BCC as a basis of upcoming research and essential information for physicians and the community.…”