Small bowel obstruction due to intraluminal metastasis from malignant melanoma

Soares, Filomena Valente; Brandão, Pedro; Correia, Raquel; Valente, Vitor Bonetti

doi:10.1093/jscr/rjz044

Cited by 4 publications

(3 citation statements)

References 7 publications

(6 reference statements)

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“…Upfront surgical procedure is indicated for the most severe cases with symptoms that need urgent treatment, such as bleeding or obstructive gastrointestinal lesions. Surgical resection can increase the long-term survival ( 13 ).…”

Section: Discussionmentioning

confidence: 99%

Primary Small Bowel Melanoma: A Case Report and Review of Literature

et al. 2022

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BackgroundThe present study analyzes diagnostic and therapeutic surgical aspects of primary small bowel melanoma, describing the clinical case and reviewing the literature. Malignant melanomas represent 1–3% of all malignant tumors of the gastrointestinal tract and are therefore uncommon. Only a few cases of metastatic melanoma (1–5%) are diagnosed in the early stages, while still asymptomatic. They show up as imaging exam findings and have better chance of treatment. Most of the time, the diagnosis is late and made in the presence of complications. The final diagnosis frequently depends on the surgical intervention after a serious complication.Case reportThis case report refers to a 55-year-old male patient, complaining of abdominal pain, blackened stools, and palpable tumor in the abdomen for ~30 days. A tomography scan was performed, which revealed the thickening and parietal enhancement of the small intestine loops with mesenteric adenomegaly and intermingled collection. For diagnostic confirmation, a laparoscopy was performed, which revealed a tumor at the jejunal level, and its resection was performed in the same act. The anatomopathological examination revealed that it was a primary small bowel melanoma.ConclusionThe bibliographic research of the small bowel melanoma demonstrated that, in this situation, the lesion can be interpreted as a primary site or metastatic lesion, considering the possibility of a single primary lesion, whose diagnosis becomes more laborious. In such cases, adjuvant therapy must be considered. The expected 5-year survival is about 9–13%.

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Section: Discussionmentioning

confidence: 99%

Primary Small Bowel Melanoma: A Case Report and Review of Literature

et al. 2022

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“…El principal factor pronóstico en pacientes con melanoma maligno en estadio IV es la localización de las metástasis a distancia. Aquellas localizadas en pulmón, hígado o tracto gastrointestinal conllevan un pronóstico peor 6 .…”

Section: Discussionunclassified

Resección laparoscópica de metástasis intestinales de melanoma maligno

et al. 2020

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Objetivos: El melanoma cutáneo presenta un alto potencial metastásico y constituye la fuente extraabdominal más frecuente de lesión del intestino delgado. El diagnóstico de metástasis gastrointestinales es a menudo una expresión de enfermedad avanzada, con una supervivencia media de entre 6 y 9 meses.Material y Métodos: Presentamos el caso un paciente varón de 63 años diagnosticado de melanoma cutáneo que acudió a urgencias por dolor abdominal y estreñimiento. Se realizó una TC abdominal donde se informó de la existencia de 2 lesiones metastásicas a nivel de intestino delgado que condicionaban oclusión intestinal.Resultados: El paciente fue intervenido quirúrgicamente bajo abordaje laparoscópico con resección de los dos segmentos intestinales afectos y anastomosis intracorpórea. El informe histopatológico confirmó que se trataban de metástasis de melanoma.Discusión y Conclusión: La oclusión intestinal por metástasis de melanoma maligno es muy infrecuente. La cirugía es el tratamiento de elección en pacientes con metástasis intestinales de melanoma. El tratamiento quirúrgico puede mejorar el pronóstico y estaría indicado casos de metástasis únicas o pacientes sintomáticos con intención paliativa. El abordaje mínimamente invasivo ofrece resultados oncológicos similares a la laparotomía.Aims: Cutaneous melanoma has a high metastatic potential, being the most frequent extra-abdominal source of small bowel metastasis. The diagnosis of gastrointestinal metastases is often an expression of advanced disease, with an average survival of 6-9 months.Material and Methods: We herein present the case of a 63-year-old male patient diagnosed with cutaneous melanoma who arrived to the emergency department complaining of abdominal pain and constipation. An abdominal CT scan was performed, it revealed two metastatic lesions in the small bowel which marked the mechanical obstruction.Results: Patient underwent a laparoscopy and both involved segments were removed. Pathology exam confirmed the diagnosis of melanoma metastases.Discussion and Conclusions: Surgery excision is the treatment of choice in patients with small bowel metastases from melanoma. Surgical management can improve the prognosis and it would be indicated in cases of single metastases or symptomatic patients with a palliative intention. Minimally invasive approach provides similar oncological results as conventional laparotomy.Small bowel obstruction due to metastases of malignant melanoma is extremely rare.

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“…Conventional X-ray imaging does not assure diagnostic advantages for metastases, but is useful to diagnose an intestinal obstruction [12]. Plain abdominal film can reveal the presence of small bowel distension with multiple air-fluid levels [13].…”

Section: Imaging Of Gastrointestinal Metastatic Melanomamentioning

confidence: 99%

Gastrointestinal metastatic melanoma: imaging findings and review of literature

Lo Mastro,

Grassi,

Reginelli

et al. 2024

J Med Imaging Intervent Radiol

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Melanoma represents approximately 5% of all the skin cancers and is well known for its ability to metastasize to a wide range of atypical locations. Organs most commonly affected by metastatic melanoma include liver, lung and brain, but spread to the gastrointestinal tract is not uncommon and small bowel involvement ranges from 51 to 71% of the cases. Given the nonspecific nature of the clinical presentation and the broad differential diagnosis, the prompt choice of imaging modality and its correct interpretation is important in order to perform a timely diagnosis. Early diagnosis and treatment of these lesions improve survival and quality of life, even in palliative cases. In this narrative review, we analyze the different imaging modalities used in the diagnosis of gastrointestinal metastases from melanoma. Typical radiological signs supporting the radiologists in interpreting images are also discussed.

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Small bowel obstruction due to intraluminal metastasis from malignant melanoma

Cited by 4 publications

References 7 publications

Primary Small Bowel Melanoma: A Case Report and Review of Literature

Primary Small Bowel Melanoma: A Case Report and Review of Literature

Resección laparoscópica de metástasis intestinales de melanoma maligno

Gastrointestinal metastatic melanoma: imaging findings and review of literature

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