Small Animal Dental, Oral and Maxillofacial Disease

Niemiec, Brook A.

doi:10.1201/b18171

Cited by 20 publications

(56 citation statements)

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“…In order to aid in the definitive diagnosis, it is possible to request complementary tests, such as: proteinogram, since the disease can present hyperproteinemia due to hypergammaglobulinaemia [7,9], consistent with chronic antigenic stimulation [6], serological and virological analyzes, radiographic examination to identify odontoclastic reabsorption lesions, periodontal disease and eventual dental tips retained within the alveoli [7,9]. The development of FLPG leads to characteristic macroscopic and microscopic findings, presenting distinct lesions and cellular components.…”

Section: Discussionmentioning

confidence: 99%

“…The affected animals exhibit varying degrees of inflammatory lesion, usually showing worsening with the evolution of the disease [7] and causing ulceration and/or proliferation of the local epithelium. Clinical signs consist of halitosis, anorexia, inappetence, dysphagia, selective appetite, variable degree of algia, weight loss, dehydration, ptyalism, with eventual associated hemorrhage, chewing of face, reduction of toilet habits and, sometimes, exteriorization of tongue [1,2,[5][6][7][9][10][11]. Macroscopic lesions tend to be multifocal to diffuse, not limited to a single mass [5], being bilateral and symmetrical, eventually presenting hemorrhagic areas.…”

Section: Discussionmentioning

confidence: 99%

“…In order to achieve this objective, it was suggested a proper oral hygiene in cases 2 and 3, aiming at the reduction of bacterial plaque and, consequently, the decline of the inflammatory stimulus, a conduct proposed by some studies [1,2,6,7,9,11]. It has been recommended the introduction of diets that reduce tartar formation and present hypoallergenic characteristics [1,9].…”

Section: Discussionmentioning

confidence: 99%

“…It is an idiopathic disease and is believed to be multifactorial [8,[10][11][12]14]. The disease presents aggressive behavior [5], characterized by intense inflammation, erythema, ulceration areas and gingival hyperplasia [1,2,5,7,11], eventually reaching glossopalatine arches (isthmus of the fauces), palate, and bucal mucosa [2,5,7,11,12,14]. Odontoclastic reabsorption is frequently observed due to the inflammatory reaction, which may lead to dental loss [1,2,11].…”

Section: Introductionmentioning

confidence: 99%

“…Due to the algia related to the clinical condition, anesthesia or sedation may be necessary to accomplish an appropriate physical examination [11]. The definitive diagnosis is established by histopathology, which reveals the presence of lymphoplasmacytic infiltrate [1,6,7,14], often accompanied by Mott cells and mast cell infiltrate.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Feline Lymphoplasmacytic Gingivostomatitis: Clinical and Anatomopathological Aspects

Sakis

Machado

Setim

et al. 2019

Acta Scientiae. Vet.

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Background: Feline lymphoplasmacytic gingivostomatitis (FLPG) is an idiopathic, multifactorial and highly challenging condition, since the results of the available treatments are partial and transitory. A set of lesions triggered by inflammatory reaction is observed, sometimes with ulcerations in the oral mucosa, leading to algia and discomfort. Histopathological examination figures as the definitive diagnostic tool, presenting distinct cellular elements. The present study aims to report three cases of FLPG, firstly addressing the anatomopathological findings, as well as the therapeutic approach used and the results obtained in each case. Cases: Case 1-Occurred in a feline Siamese male 15-year-old, weighing 3.8 kg, which was admitted at a local clinic, under the complaint of prostration, dysphagia, and weight loss, signs that were noticed approximately 5 days before. Clinical evaluation revealed multiple proliferative and ulcerative lesions, extending until the isthmus of the fauces, erythematous areas around the teeth and multifocal gingival reabsorption. Once the clinical signs and lesions were observed, samples were collected for histopathological examination and sent to the Laboratory of Animal Pathology (LAP) of Faculty of Agronomy and Veterinary Medicine of the University of Passo Fundo (FAVM-UPF). Histologically, both fragments presented lymphoplasmacytic infiltration, with large and intensely eosinophilic cytoplasm, often with granular aspect, central to lateralized hyperchromatic nuclei, located predominantly in lamina propria and mucosa, as well as a discrete Mott cell infiltrate. It was also observed the presence of diffuse suppurative chronic inflammatory infiltrate, predominantly in lamina propria and mucosa, as well as foci of edema and hemorrhage, in addition to loss of tissue architecture establishing the definitive diagnosis of FLPG. The tutor went to another veterinarian for a second opinion, but the patient died within four months. Case 2-Occurred in a no defined-breed male feline 7-year-old, weighing 3.9 kg, on complaint of hyporexia, inappetence, progressive thinning and greasy-looking fur. The tutor reported that the patient showed an increasing disinterest for offered feed, for approximately three weeks, but in recent days, consumption had declined dramatically. Clinical evaluation showed the same pattern of lesions in case 1, but with higher intensity, especially in the fauces area, as well as multifocal periodontal lesion and gingival retraction areas in several teeth. After the clinical signs and lesions were observed, samples were collected for histopathological examination and sent to the LAP of the FAVM-UPF, having the same diagnosis of case 1. The patient was submitted to a complete teeth extraction and, up to date, is asymptomatic, with a positive evolution. Case 3-Occurred in a no defined-breed female feline 6-year-old, weighing 4.1 kg, showing bleeding gums, reluctance to eat and mild halitosis, signs noticed around two weeks before. The patient was submitted to clinical evaluatio...

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Section: Discussionmentioning

confidence: 99%