Slow wave sleep and accelerated forgetting

Atherton, Kathryn; Nobre, Anna C.; Lázár, Alpár S.; Wulff, Katharina; Whittaker, Roger G.; Dhawan, V.; Lázár, Zsolt I.; Zeman, Adam; Butler, Chris

doi:10.1016/j.cortex.2016.08.013

Cited by 25 publications

(25 citation statements)

References 99 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, the negative correlation we detected between % SWS and overnight retention of the RCFT is similar to results by Atherton and colleagues [57] in patients with transient epileptic amnesia. They found %SWS to be negatively correlated with overnight sleep benefit for word pair retention in the patients (but not in healthy controls).…”

Section: Discussionsupporting

confidence: 92%

The impact of sleep characteristics and epilepsy variables on memory performance in patients with focal seizures

Schalkwijk

Ricci

Nikpour

et al. 2018

Epilepsy & Behavior

View full text Add to dashboard Cite

Disturbed sleep can negatively affect overnight memory retention as well as new learning the subsequent day. In healthy participants, positive associations between memory performance and sleep characteristics (e.g., time spent in slow-wave sleep [SWS]) have been detected. In a previous study, we found that SWS was much reduced in patients with focal seizures, but when correlations between memory complaints and various sleep characteristics were considered, the only significant relationship was with the time to onset of rapid eye movement (REM) sleep (i.e., REM latency). In this study, we investigated the relationships between sleep, epilepsy, and objective memory performance variables. Twenty-five patients with focal seizures had their memory tested while undergoing a two-day ambulatory electroencephalography (EEG). The sleep variables of interest were the percentage of time spent in SWS (%SWS) and REM latency. Epilepsy variables included the presence of (1) seizures, (2) interictal epileptiform discharges, and/or (3) hippocampal lesions as well as site of seizure origin (temporal vs extratemporal). Overnight retention (of autobiographical events, a story, and a complex geometric figure) and the ability to learn a word list on day 2 were the measures of memory. A significant positive correlation was found between word-list learning and %SWS during the previous night. A significant negative correlation was observed between REM latency and overnight retention of autobiographical events. Overnight retention scores for the story and geometric figure were not related to sleep characteristics but were negatively affected by the presence of epileptiform activity. Story retention was also worse for temporal lobe epilepsy (TLE) than for patients with extratemporal epilepsy (ETE). Those with hippocampal lesions were more impaired than those without lesions on word-list learning, autobiographical events' retention, and story retention. When multiple contributing factors were entered into regression analyses, %SWS was found to be the best predictor of subsequent word-list learning, whereas the presence of a hippocampal lesion was the best predictor of overnight retention of autobiographical events and a story. These findings provide further evidence of the ways in which particular sleep characteristics are associated with memory and suggest that treatment of sleep disturbances in patients with epilepsy might be helpful for improving their performance.

show abstract

Section: Discussionsupporting

confidence: 92%

The impact of sleep characteristics and epilepsy variables on memory performance in patients with focal seizures

Schalkwijk

Ricci

Nikpour

et al. 2018

Epilepsy & Behavior

View full text Add to dashboard Cite

show abstract

“…Whilst group differences in the magnitude of association between sleep variables and behavioural measures should be interpreted cautiously (e.g., as a consequence of small sample sizes), the view that sleep may support the consolidation of vocabulary learning to a lesser extent in children with dyslexia is consistent with previous findings from other populations with learning difficulties (e.g., Adi‐Japha, Strulovich‐Schwartz, & Julius, ; Henderson et al., ). For example, a recent study with adults who have accelerated forgetting due to epilepsy demonstrated that similar patterns of consolidation on behavioural measures can mask differences in neural processes (Atherton et al., ). Both patient and control groups showed similar patterns of recall across all testing sessions, but whereas consolidation was positively related to slow wave sleep duration in the controls, there was a negative relationship for patients.…”

Section: Discussionmentioning

confidence: 99%

Consolidation of vocabulary is associated with sleep in typically developing children, but not in children with dyslexia

Smith

Gaskell

Weighall

et al. 2017

Developmental Science

View full text Add to dashboard Cite

Sleep is known to play an active role in consolidating new vocabulary in adults; however, the mechanisms by which sleep promotes vocabulary consolidation in childhood are less well understood. Furthermore, there has been no investigation into whether previously reported differences in sleep architecture might account for variability in vocabulary consolidation in children with dyslexia. Twenty-three children with dyslexia and 29 age-matched typically developing peers were exposed to 16 novel spoken words. Typically developing children showed overnight improvements in novel word recall; the size of the improvement correlated positively with slow wave activity, similar to previous findings with adults. Children with dyslexia showed poorer recall of the novel words overall, but nevertheless showed overnight improvements similar to age-matched peers. However, comparisons with younger children matched on initial levels of novel word recall pointed to reduced consolidation in dyslexics after 1 week. Crucially, there were no significant correlations between overnight consolidation and sleep parameters in the dyslexic group. This suggests a reduced role of sleep in vocabulary consolidation in dyslexia, possibly as a consequence of lower levels of learning prior to sleep, and highlights how models of sleep-associated memory consolidation can be usefully informed by data from typical and atypical development.

show abstract

“…Retroactive interference accounts of forgetting argue that learning and mental activity that occurs after encoding contributes to memory loss (Wixted 2004). Consistent with this view, rates of forgetting are typically reduced across sleep relative to wakefulness (Jenkins and Dallenbach 1924;Newman 1938; Barrett and Ekstrand 1972;Plihal and Born 1997;Gais et al 2006;Tucker et al 2006;Tamminen et al 2010;Payne et al 2012;Atherton et al 2016;Cairney et al 2018a,b), as sleep shelters new memories from competing information.…”

mentioning

confidence: 96%

Sleep deprivation induces fragmented memory loss

et al. 2020

View full text Add to dashboard Cite

Sleep deprivation increases rates of forgetting in episodic memory. Yet, whether an extended lack of sleep alters the qualitative nature of forgetting is unknown. We compared forgetting of episodic memories across intervals of overnight sleep, daytime wakefulness, and overnight sleep deprivation. Item-level forgetting was amplified across daytime wakefulness and overnight sleep deprivation, as compared to sleep. Importantly, however, overnight sleep deprivation led to a further deficit in associative memory that was not observed after daytime wakefulness. These findings suggest that sleep deprivation induces fragmentation among item memories and their associations, altering the qualitative nature of episodic forgetting.

show abstract

Slow wave sleep and accelerated forgetting

Cited by 25 publications

References 99 publications

The impact of sleep characteristics and epilepsy variables on memory performance in patients with focal seizures

The impact of sleep characteristics and epilepsy variables on memory performance in patients with focal seizures

Consolidation of vocabulary is associated with sleep in typically developing children, but not in children with dyslexia

Sleep deprivation induces fragmented memory loss

Contact Info

Product

Resources

About