Slow Resolution of Clinically Active Trachoma Following Successful Mass Antibiotic Treatments

Keenan, Jeremy D.

doi:10.1001/archophthalmol.2011.46

Cited by 37 publications

(33 citation statements)

References 4 publications

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“…It is possible that there is a much tighter correlation of clinical signs with infection before MDA. 2,4,19 It would be worthwhile to consider whether the HRS have value at the outset of mapping in low-prevalence areas for identifying communities with little or no infection.…”

Section: Discussionmentioning

confidence: 99%

Can Clinical Signs of Trachoma Be Used after Multiple Rounds of Mass Antibiotic Treatment to Indicate Infection?

Muñoz

Stare

Mkocha³

et al. 2011

Invest. Ophthalmol. Vis. Sci.

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Section: Discussionmentioning

confidence: 99%

Can Clinical Signs of Trachoma Be Used after Multiple Rounds of Mass Antibiotic Treatment to Indicate Infection?

Muñoz

Stare

Mkocha³

et al. 2011

Invest. Ophthalmol. Vis. Sci.

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“…The most likely reason for this finding is the long duration of clinically active trachoma, especially in areas with hyperendemic trachoma. 21 Thus, in this Ethiopian setting, a follow-up period of 1 year may not be sufficiently long enough to detect a reduction in the clinical signs of trachoma.…”

Section: Discussionmentioning

confidence: 98%

The Association between Latrine Use and Trachoma: A Secondary Cohort Analysis from a Randomized Clinical Trial

Haile¹,

Tadesse²,

Gebreselassie³

et al. 2013

The American Society of Tropical Medicine and Hygiene

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Abstract. Latrine use has been promoted as a component of an integrated strategy for trachoma control. As part of a randomized trial in Ethiopia, 12 communities received a mass azithromycin distribution followed by a latrine promotion intervention. A random sample of children ages 0-9 years in each community was monitored longitudinally for ocular chlamydia. After latrine construction ended, those communities with a higher proportion of households using latrines were more likely to experience a reduction in the prevalence of ocular chlamydia. Specifically, for each 10% increase in latrine use, there was a 2.0% decrease (95% confidence interval = 0.2-3.9% decrease) in the community prevalence of ocular chlamydia over the subsequent year (P = 0.04).

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“…Clinical signs may persist long after the infection has cleared [44], and so the existence of clinical disease with no detectable infection has led some to question whether the clinical signs should be the criterion to determine when to stop treatment [45].…”

Section: Treatmentmentioning

confidence: 99%

Trachoma as cause of blindness: literature review

Silva¹,

Andrade²,

Oliveira³

et al. 2017

int arch med

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This is a literature review that used as database articles in websites like Bireme, SciELO, LILACS, Journals and Webartigos. Development:Trachoma is an ocular inflammatory disease, whose etiological agent is Chlamydia trachomatis, which affects the conjunctiva and cornea causing a chronic relapsing keratoconjunctivitis, in the course of time may lead to the formation of entropion, trichiasis and possible blindness. Its transmission occurs in the home environment, directly or indirectly. The occurrence of trachoma is mostly where hygiene and lifestyle habits are precarious. According to the World Health Organization, there are six million people currently infected.

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Slow Resolution of Clinically Active Trachoma Following Successful Mass Antibiotic Treatments

Cited by 37 publications

References 4 publications

Can Clinical Signs of Trachoma Be Used after Multiple Rounds of Mass Antibiotic Treatment to Indicate Infection?

Can Clinical Signs of Trachoma Be Used after Multiple Rounds of Mass Antibiotic Treatment to Indicate Infection?

The Association between Latrine Use and Trachoma: A Secondary Cohort Analysis from a Randomized Clinical Trial

Trachoma as cause of blindness: literature review

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