Sleepiness/Alertness on a Simulated Night Shift Following Sleep at Home with Triazolam

Walsh, James K.; Schweitzer, Paula K.; Anch, A. Michael; Muehlbach, Mark J.; Jenkins, Nancy A.; Dickins, Q. S.

doi:10.1093/sleep/14.2.140

Cited by 83 publications

(37 citation statements)

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“…Hypnotics such as temazepam 20 mg, 63 triazolam, 64 and zolpidem 65 taken after night shift work have been shown to improve day sleep quality under simulated conditions, but do not improve shift work performance. These medications should be reserved for …”

Section: Hypnotics After Workmentioning

confidence: 99%

Sleep and circadian misalignment for the hospitalist: A review

Schaefer

Williams

Zee

2012

Journal of Hospital Medicine

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Shift work is necessary for hospitalists to provide on‐site 24‐hour patient care. Like all shift workers, hospitalists working beyond daylight hours are subject to a misalignment between work obligations and the endogenous circadian system, which regulates sleep and alertness patterns. With chronic misalignment, sleep loss accumulates and can lead to shift work disorder or other chronic medical conditions. Hospitalists suffering from sleep deprivation also risk increased rates of medical errors. By realigning work and circadian schedules, a process called circadian adaptation, hospitalists can limit fatigue and potentially improve safety. Adaptation strategies include improving sleep hygiene before work, caffeine use at the start of the night shift, bright light exposure and planned naps during the shift, and short‐term use of a mild hypnotic after night work. If these attempts fail and chronic fatigue persists, then a diagnosis of shift work disorder should be considered, which can be treated with stronger pharmacotherapy. Night float scheduling strategies may also help to limit chronic sleep loss. More research is urgently needed regarding the sleep patterns and job performance of hospitalists working at night to improve scheduling decisions and patient safety. Journal of Hospital Medicine 2012; © 2012 Society of Hospital Medicine

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Section: Hypnotics After Workmentioning

confidence: 99%

Sleep and circadian misalignment for the hospitalist: A review

Schaefer

Williams

Zee

2012

Journal of Hospital Medicine

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“…Several simulation studies of shift work have shown increased daytime sleep following administration of hypnotics such as triazolam, zopiclone, flunitrazepam, estazolam, and temazepam in the morning (102)(103)(104)(105)(106)(107), but findings regarding alertness or performance-enhancing effects on the following night shift are more equivocal. Some studies have reported no improvement (104,108) while others have noted improved alertness and performance (102,105,106). In one study of actual night workers, triazolam was found to increase daytime sleep, but unfortunately sleepiness or performance during the night work was not examined (109).…”

Section: Sleep Medicationmentioning

confidence: 99%

Measures to counteract the negative effects of night work

Pallesen¹,

Bjorvatn²,

Magerøy³

et al. 2009

Scand J Work Environ Health

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“…[53][54][55][56][57][58] While one of the simulation protocols noted additional benefit in the ability to maintain alertness, 55 two others noted no changes in sleepiness. 53,54 No impairments in post sleep psychomotor performance were found subsequent to administration of 7.5 mg zopiclone, a long-acting hypnotic. 58 …”

Section: Hypnoticsmentioning

confidence: 99%

Circadian rhythm sleep disorders

Kolla¹,

Auger²,

Morgenthaler³

2012

CPT

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Misalignment between endogenous circadian rhythms and the light/dark cycle can result in pathological disturbances in the form of erratic sleep timing (irregular sleep-wake rhythm), complete dissociation from the light/dark cycle (circadian rhythm sleep disorder, free-running type), delayed sleep timing (delayed sleep phase disorder), or advanced sleep timing (advanced sleep phase disorder). Whereas these four conditions are thought to involve predominantly intrinsic mechanisms, circadian dysrhythmias can also be induced by exogenous challenges, such as those imposed by extreme work schedules or rapid transmeridian travel, which overwhelm the ability of the master clock to entrain with commensurate rapidity, and in turn impair approximation to a desired sleep schedule, as evidenced by the shift work and jet lag sleep disorders. This review will focus on etiological underpinnings, clinical assessments, and evidence-based treatment options for circadian rhythm sleep disorders. Topics are subcategorized when applicable, and if sufficient data exist. The length of text associated with each disorder reflects the abundance of associated literature, complexity of management, overlap of methods for assessment and treatment, and the expected prevalence of each condition within general medical practice.

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Sleepiness/Alertness on a Simulated Night Shift Following Sleep at Home with Triazolam

Cited by 83 publications

References 0 publications

Sleep and circadian misalignment for the hospitalist: A review

Sleep and circadian misalignment for the hospitalist: A review

Measures to counteract the negative effects of night work

Circadian rhythm sleep disorders

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