Sleep quality and asthma control and quality of life in non-severe and severe asthma

Abstract

Purpose The effect of sleep quality on asthma control independent from common comorbidities like gastroesophageal reflux disease (GERD) and obstructive sleep apnea (OSA) is unknown. This study examined the association between sleep quality and asthma control and quality of life after accounting for OSA and GERD in non-severe (NSA) and severe (SA) asthma. Methods Cross-sectional data from 60 normal controls, 143 with NSA, and 79 with SA participating in the Severe Asthma Research Program was examined. Those who reported using positive airway pressure therapy or were at high risk for OSA were excluded. Results Both SA and NSA had poorer sleep quality than controls, with SA reporting the worst sleep quality. All asthmatics with GERD and 92% of those without GERD had poor sleep quality (p =.02). The majority (88%–100%) of NSA and SA participants who did not report nighttime asthma disturbances still reported having poor sleep quality. In both NSA and SA, poor sleep quality was associated with worse asthma control and quality of life after controlling for GERD and other covariates. Conclusions These results suggest that poor sleep quality is associated with poor asthma control and quality of life among asthmatics and cannot be explained by comorbid GERD and nighttime asthma disturbances.

Associations between allergic diseases and attention deficit hyperactivity/oppositional defiant disorders in children

“…It has been documented that parental marital conflicts (22), low socioeconomic status (23), household second-hand smoke or prenatal tobacco exposure (24), and preterm birth are related to ADHD or ODD. However, two limitations of this study deserve discussion.…”

Association Between Insomnia and Asthma Burden in the Severe Asthma Research Program (SARP) III

“…Previous studies suggest that sleep difficulties persist even in those without asthma-related nocturnal awakenings, with 20% to 46% reporting moderate to severe difficulty staying asleep. 7,10,12 These data suggest that poor sleep may not solely be due to nighttime asthma awakenings, but may represent comorbid insomnia. Insomnia disorder is characterized by selfreported difficulty falling asleep, staying asleep, or poor quality sleep and accompanying daytime symptoms such as fatigue, irritability, and impaired concentration.…”

“…[7][8][9][10][11][12] Sleep difficulties are often considered a consequence of nocturnal awakenings resulting from nighttime asthma symptoms and/or the need for rescue inhaler medication, which will resolve with adequate control of asthma symptoms. Previous studies suggest that sleep difficulties persist even in those without asthma-related nocturnal awakenings, with 20% to 46% reporting moderate to severe difficulty staying asleep.…”

Reflux, Allergic Rhinitis, and Sleep Disorders with Asthma Control and Quality of Life

“…Recent studies reported that, asthma is more difficult to control in the obese patient [41][42][43], since different type of airway inflammation, obesity related comorbidities such as obstructive sleep apnea [2]. Luyster and his colleagues showed that, poor sleep quality is associated with poor asthma control and quality of life among asthmatics [44]. Similar to Luyster's result, in our study we found that there was negative correlation between ACT and PSQI (r=-0,620; p<0.001).…”