Sleep duration and chronic kidney disease: The Korean Genome and Epidemiology Study (KoGES)-Kangwha study

Abstract

Background/AimsSleep duration affects health in various ways. The objective of this study was to investigate the associations of sleep duration with chronic kidney disease (CKD) in a Korean adult population.MethodsThis cross-sectional analysis was conducted for total of 1,360 participants who completed baseline health examinations for the Korean Genome and Epidemiology Study-Kangwha study in 2010 to 2011. Sleep habits were measured by an interviewer-assisted questionnaire. Sleep duration was calculated based on the number of hours per day participants had slept over the past 1 year. CKD was defined as either proteinuria or estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2. Multiple logistic regression models were applied to examine associations between sleep duration and CKD.ResultsWomen with very long sleep duration (≥ 9 hours/day) were at significantly increased odds for having high serum creatinine (odds ratio [OR], 2.936; 95% confidence interval [CI], 1.176 to 7.326), low eGFR (OR, 3.320; 95% CI, 1.372 to 8.034), and CKD (OR, 3.112; 95% CI, 1.315 to 7.363), compared those with a typical sleep duration (7 to < 8 hours/day), after adjusting for sociodemographic status, socioeconomic status, health behaviors, comorbidities, and sleep quality. Among women, for every 1 hour increase in sleep duration per day, there was a 24.6% increase in the presence of CKD (OR, 1.246; 95% CI, 1.019 to 1.523). However, among men, sleep duration was not significantly associated with CKD.ConclusionsVery long sleep duration was independently associated with a higher prevalence of CKD among Korean women. Gender may influence this association.

Association between Sleep Duration and Body Composition Measures in Korean Adults: The Korea National Health and Nutrition Examination Survey 2010

“…One study suggested that sleep duration may be associated with cardiometabolic outcomes, but only in women [ 24 ]. A recent study conducted in Korea found that long sleep duration was associated with a higher prevalence of chronic kidney disease among Korean women, whereas no significant relationship was noted in men [ 25 ]. Further detailed studies are needed to examine the exact mechanism of sex-specific disorders related to sleep duration.…”

Diet and Sleep Physiology: Public Health and Clinical Implications

“…Finally, there is emerging evidence regarding the association between long sleep duration, usually defined as more than 9 h of sleep, and chronic disease ( 49 – 51 ). Long sleep duration has been associated with higher risk of CVD, type 2 diabetes, depression, obesity, and chronic kidney disease in trials and observational studies ( 29 , 49 – 53 ). However, the mechanisms for these relationships are not clear ( 49 , 50 ).…”

Self-reported sleep duration and daytime napping are associated with renal hyperfiltration in general population

“…Previous research has found that self-reported habitual sleep duration is associated with prevalent and incident CKD (Turek et al, 2012). Studies have found that the prevalence of kidney disease or renal hyperfiltration was higher in those reporting short sleep durations as well as in those reporting long sleep durations compared with those sleeping 7-8 h per night (Cheungpasitporn et al, 2016;Kim et al, 2017;Lin et al, 2017;Salifu et al, 2014), although one study only observed this association in women (Choi et al, 2017). Further, the incidence of proteinuria was greater among people reporting shorter sleep duration (≤5 h per night) in a sample of employees of Osaka University in Japan (Yamamoto et al, 2012).…”