Self-reported sleep duration and daytime napping are associated with renal hyperfiltration in general population

Lin, Miao; Su, Qing; Wen, Junping; Wei, Shichao; Yao, Jin; Huang, Huibin; Liang, Jing; Li, Liantao; Lin, Wei; Li, Lin; Lu, Jieli; Bi, Yufang; Wang, Weiqing; Ning, Guang; Chen, Gang

doi:10.1007/s11325-017-1470-0

Cited by 21 publications

(23 citation statements)

References 51 publications

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“…Napping habit was reported by 7,001 of 11,198 men (62.5%) and 15,456 of 22,652 women (68.2%). Those who took naps seem to more likely to be women, which is converse to previous study 27 . Individuals who took naps were more likely to be regular drinkers, smokers and to have less physic exercise, naturally, they also have higher BMI and TG values and were more likely to have metabolic disease like obesity, hypertension, especially diabetes.…”

Section: Resultscontrasting

confidence: 85%

Self-reported sleep duration and daytime napping are associated with renal hyperfiltration and microalbuminuria in apparently healthy Chinese population

Zhang

Yan

et al. 2019

Preprint

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The word count of the manuscript and abstract are 3404 and 247. Abstract 2 Background: Sleep duration affects health in various way. The objective of this study 3 was to investigate the relationship between sleep duration, daytime napping and kidney 4 function in a middle-aged apparently healthy Chinese population.5Methods: According to self-reported total sleep and daytime napping duration, 33,850 6 participants aged 38 to 90 years old from 8 regional centers were divided into subgroups. 7 Height, weight, waistline, hipline, blood pressure, biochemical index, FBG, PBG, 8 HbA1c, creatinine and urinary albumin-creatinine ratio (UACR) were measured and 9 recorded in each subject. Microalbuminuria was defined as UACR>=30 mg/g, CKD 10 was defined as eGFR<60 ml/min and hyperfiltration was defined as eGFR>=135 11 ml/min. Multiple logistic regressions were applied to investigate associations between 12 sleep and kidney function. 13Results: Compared to participants with [7-8]h/day sleep, ORs of >9 h/day, (8, 9]h/day 14 and <6h/day sleep for microalbuminuria were 1.317 (1.200-1.446, p<0.001), 1.215 15 (1.123-1.315, p<0.001) and 1.218 (0.967-1.534, p=0.094). eGFR levels were U-shaped 16 associated with sleep duration among subjects with >=90ml/min eGFR, and N-shaped 17 associated with sleep duration among subjects with <90ml/min eGFR. OR of >9h/day 18 sleep for hyperfiltration was 1.400 (1.123-1.745, p=0.003) among eGFR>=90 ml/min 19 participants. Daytime napping had a negative effect on renal health. Compared to 20 participants did not have napping habit, the ORs of (0，1]h/day, (1，1.5]h/day and 21 >1.5h/day daytime napping for microalbuminuria were 1.477 (1.370-1.591, p<0.001), 22 1.217 (1.056, 1.403, p=0.007) and 1.447 (1.242, 1.687, p<0.001). 23 Conclusions: Total sleep duration are U-shaped associated with renal health outcomes. 24 Daytime napping had a negative effect on renal health. 25 42reported inappropriate sleep duration contributes to glomerular hyperfiltration 13,26-28 . 43 This difference in outcomes can be attributed not only to differences in race, age, social 44 work stress, health and economic status of the participants, but also to the fact that in 45 the progression of CKD, healthy individuals tend to have glomerular hyperfiltration 46 initially, followed by increased risk for renal injury, leading to a decrease in filtration 47 Study subjects: A total of 33,850 participants from 8 regional centers include in the 57 REACTION (Risk Evaluation of cAncers in Chinese diabeTic Individuals a 58 LONgitudinal) study, in which are Dalian, Guangzhou, Zhengzhou, Lanzhou, Luzhou, 59 Wuhan, Guangxi, and Shanghai. Excluded participants with primary kidney diseases, 60 daily ACEI/ARB medicine use, and those with a fallacious self-reported sleep duration 61 (<4 h or >12 h).62 Questionnaire: A standardized questionnaire was used to collect basic information 63 including medical history, physical exercise, and smoking and drinking habits. Self-64 reported sleep duration and daytime napping time were ascertained...

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Section: Resultscontrasting

confidence: 85%

Self-reported sleep duration and daytime napping are associated with renal hyperfiltration and microalbuminuria in apparently healthy Chinese population

Zhang

Yan

et al. 2019

Preprint

Self Cite

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“…31 It is notable that hyperfiltration was recently found also to increase arterial stiffness in the population without diabetes and, given that stiffer arteries in general increase CVD risk, these data suggest that hyperfiltration is linked to CVD morbidity and mortality even in the absence of albuminuria. 32 Whether there is a direct effect of hyperglycaemia on the CVD risk in T1D has been a matter of debate. 9,33,34 In the present study, HbA1c was a predictor of CAD but not of stroke in those with normoalbuminuria, and every 1-unit increase in HbA1c increased the risk of CAD by 22% in the participants with normoalbuminuria (data not shown).…”

Section: Discussionmentioning

confidence: 99%

Risk of coronary artery disease and stroke according to sex and presence of diabetic nephropathy in type 1 diabetes

Harjutsalo

Thomas

Forsblom

et al. 2018

Diabetes Obesity Metabolism

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“…In hamsters, for example, prolonged circadian disorganization may be associated with proteinuria, tubular dilation, and cellular apoptosis [23]. More recently, in humans, daytime napping has been suggested as being associated with negative effects on renal function, namely hyperfiltration and microalbuminuria [24,25]. How these issues directly link to the traveling athlete remains to be determined.…”

Section: Effect Of Jet Lag and Long-haul Flight On Gastrointestinal Amentioning

confidence: 99%

“…And yet, Schumacher and co-authors [28] did not measure any urinary indices of hydration status in their work (Table 1). [24,25] No data are available to make a clear estimation…”

Section: Fluid Intake and Hydration Status Of Athletes On Long-haul Fmentioning

confidence: 99%

Up in the Air: Evidence of Dehydration Risk and Long-Haul Flight on Athletic Performance

2020

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The microclimate of an airline cabin consists of dry, recirculated, and cool air, which is maintained at lower pressure than that found at sea level. Being exposed to this distinctive, encapsulated environment for prolonged durations, together with the short-term chair-rest immobilization that occurs during long-haul flights, can trigger distinct and detrimental reactions to the human body. There is evidence that long-haul flights promote fluid shifts to the lower extremity and induce changes in blood viscosity which may accelerate dehydration, possibly compromising an athlete’s potential for success upon arrival at their destination. Surprisingly, and despite several recent systematic reviews investigating the effects of jet lag and transmeridian travel on human physiology, there has been no systematic effort to address to what extent hypohydration is a (health, performance) risk to travelers embarking on long journeys. This narrative review summarizes the rationale and evidence for why the combination of fluid balance and long-haul flight remains a critically overlooked issue for traveling persons, be it for health, leisure, business, or in a sporting context. Upon review, there are few studies which have been conducted on actual traveling athletes, and those that have provide no real evidence of how the incidence rate, magnitude, or duration of acute dehydration may affect the general health or performance of elite athletes.

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Self-reported sleep duration and daytime napping are associated with renal hyperfiltration in general population

Abstract: Sleep duration less than 6 h/day or more than 10 h/day and long daytime napping tend to be associated with an increased risk of renal hyperfiltration in middle-aged general population, and this relationship was independent of diabetes, hypertension, obesity, or poor sleep quality.

Cited by 21 publications

References 51 publications

Self-reported sleep duration and daytime napping are associated with renal hyperfiltration and microalbuminuria in apparently healthy Chinese population

Self-reported sleep duration and daytime napping are associated with renal hyperfiltration and microalbuminuria in apparently healthy Chinese population

Risk of coronary artery disease and stroke according to sex and presence of diabetic nephropathy in type 1 diabetes

Up in the Air: Evidence of Dehydration Risk and Long-Haul Flight on Athletic Performance

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