Sleep disturbances and quality of life in Sub-Saharan African migraineurs

Abstract

BackgroundAlthough in the past decade occidental countries have increasingly recognized the personal and societal burden of migraine, it remains poorly understood in Africa. No study has evaluated the impact of sleep disturbances and the quality of life (QOL) in sub-Saharan Africans with migraine.MethodsThis was a cross-sectional study evaluating adults, ≥ 18 years of age, attending outpatient clinics in Ethiopia. Standardized questionnaires were utilized to collect demographic, headache, sleep, lifestyle, and QOL characteristics in all participants. Migraine classification was based on International Classification of Headache Disorders (ICHD)-II criteria. The Pittsburgh Sleep Quality Index (PSQI) and the World Health Organization Quality of Life (WHOQOL-BREF) questionnaires were utilized to assess sleep quality and QOL characteristics, respectively. Multivariable logistic regression models were fit to estimate adjusted odds ratio (OR) and 95% confidence intervals (95% CI).ResultsOf 1,060 participants, 145 (14%) met ICHD-II criteria for migraine. Approximately three-fifth of the study participants (60.5%) were found to have poor sleep quality. After adjustments, migraineurs had over a two-fold increased odds (OR = 2.24, 95% CI 1.49-3.38) of overall poor sleep quality (PSQI global score >5) as compared with non-migraineurs. Compared with non-migraineurs, migraineurs were also more likely to experience short sleep duration (≤7 hours) (OR = 2.07, 95% CI 1.43-3.00), long sleep latency (≥30 min) (OR = 1.97, 95% CI 1.36-2.85), daytime dysfunction due to sleepiness (OR = 1.51, 95% CI 1.12-2.02), and poor sleep efficiency (<85%) (OR = 1.93, 95% CI 1.31-2.88). Similar to occidental countries, Ethiopian migraineurs reported a reduced QOL as compared to non-migraineurs. Specifically Ethiopian migraineurs were more likely to experience poor physical (OR = 1.56, 95% CI 1.08-2.25) and psychological health (OR = 1.75, 95% CI 1.20-2.56), as well as poor social relationships (OR = 1.56, 95% CI 1.08-2.25), and living environments (OR = 1.41, 95% CI 0.97-2.05) as compared to those without migraine.ConclusionSimilar to occidental countries, migraine is highly prevalent among Ethiopians and is associated with poor sleep quality and a lower QOL. These findings support the need for physicians and policy makers to take action to improve the quality of headache care and access to treatment in Ethiopia.

Respiratory Symptoms, Sleep, and Quality of Life in Patients With Advanced Lung Cancer

“…20 Specific categories were used to define optimal and suboptimal sleep quality, including long sleep latency (<30 vs. $30 minutes), poor sleep efficiency ($85 vs. <85%), days dysfunction due to sleep (<once a week vs. $once a week), and sleep medication use during the past month (<once a week vs. $once a week). 21 The demographic characteristics measured were age, gender, marital status, and education level.…”

Association of suicidal ideation with poor sleep quality among Ethiopian adults

“…Sleep disorders, affecting more than 45% of the world’s population, have emerged as important global public health problems [5]. Individuals experiencing sleep disorders have increased risks of chronic diseases such as cancer, hypertension, diabetes, and cognitive impairment, obesity, as well as increased all-cause mortality, [6–10].…”

“…However the geographical scope of evidences is limited, with the majority of researches being conducted in higher income countries, and disproportionately little evidence coming from LAMICs [14]. Recent studies conducted in Ethiopia have documented high prevalence estimates of poor sleep quality [5], [11] in adult populations similar to those reported in other occidental countries. To the best of our knowledge, however, no study has evaluated the link between sleep quality and suicidal ideation among Ethiopians or other sub-Saharan African adults.…”

Migraine and sleep

“…В популяционном исследовании I. Morgan и соавт. [9] использовали Питтсбургский опросник определения индекса качества сна (PSQI) и опросник оценки качества жизни пациентов, разработанный ВОЗ, у больных с мигренью в сравнении с контрольной группой. Исследование показало, что приблизительно 14% пациентов испытывали мигренозные приступы.…”