Sleep disturbances among methadone maintained patients

Stein, Michael D.; Herman, Debra S.; Bishop, Shaughna; Lassor, Joanna A.; Weinstock, Marjorie C.; Anthony, James R.; Anderson, Bradley J.

doi:10.1016/s0740-5472(03)00191-0

Cited by 107 publications

(121 citation statements)

References 40 publications

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“…Several population studies have shown that 10 to 15% of people with chronic sleep disorders are also drug abusers 1 . The chronic use of drugs that cause euphoria or changes in consciousness may lead to reduced QL 2 .…”

Section: Chronic Sleep Disorders May Impair Quality Of Life (Ql)mentioning

confidence: 99%

Quality of life and sleep impairment in chronic cocaine dependents

Lima

Rossini

Reimão

2008

Arq. Neuro-Psiquiatr.

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-Objective: To evaluate quality of life (QL) and sleep quality impairment of cocaine chronic dependents in use of cocaine. Method: 40 patients, chronic cocaine dependents were evaluated (37 M; 3 F), with mean age of 28.92 years, along with 40 controls paired for gender and age. The following instruments were used: a) the semi-structured clinical interview; b) the Brazil Economic Classification; c) the Pittsburgh Sleep Quality Index; d) World Heath Organization Quality of Life-BREF (WHOQOL-BREF). Results: The cocaine dependents showed QL impairment, with deficits in the physical, psychological and social relations domains. Impaired sleep quality was also observed in the cocaine dependents. However, the QL impairment was not directly due to sleep deficit. Conclusion: Chronic cocaine dependents showed impairment in QL and sleep impairment. However, for the cocaine dependent group, sleep impairment was not regarded as compromising QL probably because cocaine, rather than sleep, was the main factor negatively influencing QL.KEy WORdS: cocaine, sleep, sleep disorders, quality of life. Qualidade de vida e comprometimento do sono em dependentes crônicos de cocaínaResumo -Objetivo: Avaliar a qualidade de vida (QV) em dependentes de cocaína na fase de uso de droga e comprometimento da qualidade do sono. Método: Foram avaliados 40 pacientes dependentes de cocaína (37 M; 3 F), com média de idade de 29,92 anos; e 40 controles, equiparando-se as variáveis de gênero e idade e utilizando-se os seguintes instrumentos: a) Entrevista clínica semi-dirigida; b) Classificação Econômica Brasil; c) Índice de Qualidade do Sono de Pittsburgh; d) World Health Organization Quality of Life-BREF (WHOQOLBreve). Resultados: Os dependentes de cocaína apresentaram prejuízo na QV, com alterações nos domínios físico, psicológico e também das relações sociais. No grupo estudo não houve associação entre QV e qualidade do sono, ou seja, para os sujeitos desta amostra, a qualidade do sono não afetou a QV. Conclusão: No grupo estudo a QV foi considerada prejudicada, mas não devida de forma primordial ao comprometimento da qualidade do sono. Nestes pacientes a cocaína é provavelmente o fator primordial negativo sobre a QV e não o comprometimento do sono. PALAVRAS-CHAVE: cocaína, sono, distúrbios do sono, qualidade de vida.

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Section: Chronic Sleep Disorders May Impair Quality Of Life (Ql)mentioning

confidence: 99%

Quality of life and sleep impairment in chronic cocaine dependents

Lima

Rossini

Reimão

2008

Arq. Neuro-Psiquiatr.

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“…5,6 Çalışmalarda opiyat bağımlılarında depresyon veya anksiyete bozukluğu eş tanısı olanların olmayanlara göre uyku kaliteleri daha kötü bulunmuştur. 7 Endojen opiyatların peptid yapılı nörohormon vasopressin ile birlikte uykunun başlatılması ve sürdürülmesinde, suprakiyazmatik nükleus tarafından düzenlenen sirkadiyen ritm üzerinden etkili oldukları var sayılmıştır. 8 Ağrı ve opiyatlar hipofiz bezinden vasopressin salınımını uyarır-lar, vasopressin de beyin omurilik sıvısına endorfinlerin salınımına neden olur.…”

Section: Introductionunclassified

“…8 OB'de, ilaç ve ruhsal-toplumsal tedavilere rağmen uyku bozuklukları sık görülmektedir. 3,7,11 Kronik reçeteli opiyat kullanan hastaların %80.6'sının uyku kalitesinin kötü olduğu bulunmuştur. 12 OB tedavisinde kullanılan metadon veya buprenorfin ile arındırma tedavisi yapılan hastaların uyku özelliklerinde bozulmalar ve farklılaşmalar olduğu, uyku latansının uzadığı ve uykunun fragmante olduğu saptanmıştır.…”

Section: Introductionunclassified

Evaluation of sleep quality of early buprenorphine/naloxone treatment in opioid addicted patients

Şipka¹,

Vardar²

2018

Anadolu Psikiyatri Derg

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“…In recent years, attention has shifted its focus to quality of sleep in methadone maintenance patients (Stein et al, 2004;Peles et al, 2006;Peles et al, 2009;Sharkey et al, 2009;Sharkey et al, 2010;Liao et al, 2011;Sharkey et al, 2011). For example, in a study that systematically studied the prevalence of sleep disorders among 135 heroin-dependent Chinese on MMT in Hunan Province, China found a majority of the patients (n = 134 subjects, 99.23%) had a total PSQI score of > 5, suggestive of sleeping problems (Liao et al, 2011).…”

Section: Introductionmentioning

confidence: 99%

“…Although a number of studies have assessed the association between patients' experiences of pain and sleep in patients on MMT (Stein et al, 2004;Peles et al, 2006;Peles et al, 2009), less is known about the relationship of patients' pain sensitivity or pain tolerance on sleep quality.…”

Section: Introductionmentioning

confidence: 99%

Objective pain sensitivity affects sleep quality in opioid dependent males on methadone maintenance therapy

Zahari

Lee

Tan

et al. 2014

Preprint

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Aim Pain associated poor sleep quality has been reported among opioid dependent patients on methadone maintenance therapy (MMT) but objective pain data are lacking.This study aimed to investigate the rate of objective pain sensitivity and the relationship between pain sensitivity and sleep quality in this susceptible male population. Methods A total of 168 male patients from MMT clinic in Kelantan, Malaysia were included into the study. Objective pain tolerance to cold pressor test (CPT) was evaluated at 0 hour and at 24 hours after the first CPT. Malay version of the Pittsburgh Sleep Quality Index -PSQI and the subjective opiate withdrawal scale (SOWS) questionnaires were administered to evaluate the quality of sleep and withdrawal symptoms, respectively. Results The mean age of the study participants was 37.22 (SD 6.20) PrePrints ABSTRACT Aim Pain associated poor sleep quality has been reported among opioid dependent patients on methadone maintenance therapy (MMT) but objective pain data are lacking. This study aimed to investigate the rate of objective pain sensitivity and the relationship between pain sensitivity and sleep quality in this susceptible male population.Methods A total of 168 male patients from MMT clinic in Kelantan, Malaysia were included into the study. Objective pain tolerance to cold pressor test (CPT) was evaluated at 0 hour and at 24 hours after the first CPT. Malay version of the Pittsburgh Sleep Quality Index -PSQI and the subjective opiate withdrawal scale (SOWS) questionnaires were administered to evaluate the quality of sleep and withdrawal symptoms, respectively. ResultsThe mean age of the study participants was 37.22 (SD 6.20)

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Sleep disturbances among methadone maintained patients

Cited by 107 publications

References 40 publications

Quality of life and sleep impairment in chronic cocaine dependents

Quality of life and sleep impairment in chronic cocaine dependents

Evaluation of sleep quality of early buprenorphine/naloxone treatment in opioid addicted patients

Objective pain sensitivity affects sleep quality in opioid dependent males on methadone maintenance therapy

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