Sleep and mood disorders in dry eye disease and allied irritating ocular diseases

Ayaki, Masahiko; Kawashima, Motoko; Negishi, Kazuno; Kishimoto, Toshifumi; Mimura, Masaru; Tsubota, Kazuo

doi:10.1038/srep22480

Cited by 61 publications

(63 citation statements)

References 29 publications

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“…The severity of dry eye disease significantly correlated with the PSQI and HADS (P < 0.05). The authors of the study demonstrated that sleep quality in patients with dry eye disease was significantly worse than in patients with other irritating ocular diseases, thus indicating a correlation with the severity of dry eye disease (11).…”

Section: Sleep Disorder In Ophthalmologymentioning

confidence: 94%

The Interface Between Psychiatry and Ophthalmology

Sadykov

Studnička

Hosák

et al. 2019

Acta Med. (Hradec Kralove, Czech Repub.)

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Objective: The aim of this article is to review the interface between psychiatry and ophthalmology at several levels, such as the influence of psychopharmacology on eye disorders, the occurrence of psychiatric symptoms in eye diseases, and the neuroophthalmological examination methods supporting the validity of psychiatric diagnoses. Materials and Methods: We searched the PubMed computer database for the key words “Psychiatry” and “Ophthalmology” on the 28th of August, 2018 to obtain relevant articles which were consequently summarized. Results: The results showed that most patients with ocular disease simultaneously have one or more psychiatric symptoms. We also found a prevalence of eye-related side effects in patients who use psychiatric drugs. At the same time, we observed that some ophthalmology methods of diagnostics can be used as diagnostic tools in psychiatry. Conclusions: Most studies showed a significant relation between psychiatry and ophthalmology, such as eye symptoms and diseases following long-term use of psychotropics as well as psychiatric symptoms and syndromes in patients with eye disorders. Our review may be beneficial to psychiatrists, ophthalmologists, and, last but not least, the patients themselves.

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Section: Sleep Disorder In Ophthalmologymentioning

confidence: 94%

The Interface Between Psychiatry and Ophthalmology

Sadykov

Studnička

Hosák

et al. 2019

Acta Med. (Hradec Kralove, Czech Repub.)

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“…Having symptoms of dry eyes and dry mouth in a non-SS setting can be associated with having other conditions such as anxiety, depression and/or other systemic diseases such as fibromyalgia. [28][29][30][31] In fact, the non-SS group had a higher reported prevalence of moderate to severe depression (39% vs 26%, p<0.001) and reported higher use of anticholinergic medication (39% vs 23%, p<0.001) than SS participants. Anticholinergic agents are a broad class of medications that include antidepressants, anxiolytics, antipsychotics, sleep aids and antihistamines/antiemetics, which themselves can produce sicca symptoms as well.…”

Section: Rmd Openmentioning

confidence: 99%

Health-related quality of life and depression among participants in the Sjögren’s International Collaborative Clinical Alliance registry

et al. 2017

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ObjectiveTo examine health-related quality of life (HRQoL) and depression among participants in an international Sjögren’s syndrome (SS) registry, comparing those with and without SS.MethodsCross-sectional study of participants in the Sjögren’s International Collaborative Clinical Alliance (SICCA) registry. The 2016 American College of Rheumatology/European League Against Rheumatism SS classification criteria were used to determine disease status. HRQoL was assessed using the Short Form 12, version 2 Health Survey to derive scores for physical component summary (PCS) and mental component summary (MCS). Depression was assessed using the 9-Item Patient Health Questionnaire. Multivariate linear and logistic regression analyses were performed to identify predictors of HRQoL and depression while controlling for potential confounders.ResultsAmong 2401 SICCA participants who had symptoms of dry eyes and dry mouth, 1051 had SS (44%) and 1350 did not (56%). After controlling for confounders, when compared with non-SS participants, those with SS had better PCS (p<0.001, β=2.43, 95% CI 1.57 to 3.29), MCS (p=0.002, β=1.37, 95% CI 0.50 to 2.23) and lower adjusted odds of depression (p<0.001, OR 0.67, 95% CI 0.55 to 0.81). Other significant predictors of HRQoL and depression included employment, country of residence and use of medication with anticholinergic effect or for management of SS-related signs and symptoms.ConclusionOur results suggest that among symptomatic patients, having a diagnosis of SS may be associated with better emotional and psychological well-being compared with patients without a diagnosis. Having a definitive diagnosis of SS may encourage patients to obtain a better understanding of their disease and have coping mechanisms in place to better manage their symptoms.

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“…It is therefore recommended that evaluation and treatment for neuropathic pain should be considered in dry eye patients [16]. Other commonly associated comorbidities in dry eye include sleep disturbances [17], anxiety and depression [18], migraine [14], rheumatological disease and allergies like sinusitis [19]. Dry eye was also found to be associated with significantly reduced happiness [20], which qualifies it as a 'lifestyle' disease.…”

Section: Dry Eye As a Clinical Problemmentioning

confidence: 99%

From Volume to Value: Prospects and Pitfalls in Organising Integrated Dry Eye Practice Units

Goh¹,

Korne²,

Tong³

2017

J Clin Exp Ophthalmol

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With the advent of aging populations, chronic multifactorial diseases will dominate and strain existing models of health care. A model of healthcare delivery that emphasizes seamless, integrated, team-based care and remuneration for patient outcomes, have proven advantageous in diseases like diabetes mellitus, compared to systems based on isolated medical services. It is, however, unclear whether major chronic ophthalmic diseases including dry eye are also suitable for this model. Multiple co-morbidities such as depression, anxiety, postmenopausal mood swings, sleep disorders, and chronic neuropathic pain in dry eye greatly and unexpectedly increase its healthcare burden, and also produce high levels of patient and physician frustration. Many patients benefit from counseling, social support, and psychological management, but are frustrated by multiple referrals and inefficiency in care coordination. With the new model, patients may have a seamless transition between care settings, better experience and improved outcomes, and likely attain added value per unit cost.Keywords: Eye diseases; Health policy; Practice guidelines as topic; Primary health care; Quality of health care Rethinking Care for Chronic DiseasesThe trend of medical sub-specialization with the development and proliferation of organ-based or medical technique-based healthcare centers has clearly benefited many generations of people in developed and even developing countries [1]. The advantages of providing highend care are mainly in single, acute problems requiring specialized skills. However, incurable and disabling chronic multi-organ diseases are increasing, due to aging of communities and partly, success of specialized disciplines in management of treatable maladies. We define chronic disease as by WONCA International Classification Committee: a health condition that is long in duration-often with long latency and protracted course, multi-factorial in aetiology, no definite cure, changes gradually over time, heterogeneous in susceptibility" [2], including the lived experience of coping with health disruption and impact on psychological and social function [3].In chronic diseases with multiple comorbidities, health-care disciplines should be integrated and centered on the patient. The "Esther network" [4] and Ed Wagner's chronic disease model [5] are examples of integration across the entire continuum of care, including self and community care, which also cater to the bio psychosocial needs of a person [6]. A study involving 113,452 unique patients evaluated the integration of primary healthcare family practice, internal medicine and geriatric practices, and found superior outcomes in terms of depression screening rates and increased adherence to care, with less emergency visits/admissions [7].The traditional model of healthcare, pivoted around specialized tertiary centers ( Figure 1A), is not optimized for chronic disease care. Traditional healthcare models are largely 'serviced-based' , whereby patients are typically charged for each i...

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Sleep and mood disorders in dry eye disease and allied irritating ocular diseases

Cited by 61 publications

References 29 publications

The Interface Between Psychiatry and Ophthalmology

The Interface Between Psychiatry and Ophthalmology

Health-related quality of life and depression among participants in the Sjögren’s International Collaborative Clinical Alliance registry

From Volume to Value: Prospects and Pitfalls in Organising Integrated Dry Eye Practice Units

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