Sleep abnormalities in juvenile myoclonic epilepsy—A sleep questionnaire and polysomnography based study

Roshan, Sujata; Puri, Vinita; Chaudhry, Neera; Gupta, Anu; Rabi, Sumit Kumar

doi:10.1016/j.seizure.2017.06.021

Cited by 41 publications

(30 citation statements)

References 41 publications

(51 reference statements)

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“…(16) Similar results not distinguishable between drug-naive and valproate-groups were shown by Ramachandraiah and colleagues: higher epileptiform discharges in N1/REM in the drug-naive group; higher Table 2.…”

Section: Dosesupporting

confidence: 74%

“…(16) Sleep instability (difficulties in initiation and maintenance of sleep) in JME patients was confirmed in many studies. According to research by P.Kristian et al, (19) which was confirmed by others, (16) patients had reduced sleep efficiency, increased sleep onset latency, and increased wake percentage. Reduced REMS was noted by S.Roshan up to the total lack of REMS at all during sleep cycles.…”

Section: Psgmentioning

confidence: 91%

“…(17) It has been demonstrated (16,18) that epileptiform discharges in NREMS, leading to arousal, form stage shifts.Several studies have evaluated such sleep parameters as sleep duration, sleep onset latency, sleep staging, wakefulness after sleep onset, sleep efficiency, REMS latency and duration, arousal index, apnea-hypopnea index, cardiac events, and periodic limb movements during sleep. (16) Sleep instability (difficulties in initiation and maintenance of sleep) in JME patients was confirmed in many studies. According to research by P.Kristian et al, (19) which was confirmed by others, (16) patients had reduced sleep efficiency, increased sleep onset latency, and increased wake percentage.…”

Section: Psgmentioning

confidence: 99%

“…Reduced REMS was noted by S.Roshan up to the total lack of REMS at all during sleep cycles. (16) The purpose of this review was to evaluate scientific literature on management of SDs in JME.…”

Section: Psgmentioning

confidence: 99%

“…(16) These are precisely the unfavorable factors facing a patient-teenager, besides JME. JME is a socially significant disease with poor long-term social outcome after 25 years, including depression, social isolation, and underemployment.…”

Section: The Epilepsy Itselfmentioning

confidence: 99%

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Advances in the Management of Sleep Disorders in Juvenile Myoclonic Epilepsy

Moskaleva¹,

Шилкина²,

Shnayder³

et al. 2018

IJBM

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Juvenile myoclonic epilepsy (JME) is a well-defined sub-syndrome of idiopathic generalized/genetic epilepsy, usually presenting in adolescence and characterized by myoclonic jerks, predominately in the arms, associated with tonic-clonic seizures and less often generalized absences. Although the evidence base for a relationship between JME and sleep disorders is weak, most experts regard sleep disorders as an actual comorbidity. This paper reviews the literature underpinning the development of sleep disorders in JME patients. Data that report associated causes of sleep problems in JME patients are discussed, as is the importance of counseling on lifestyle issues. Lastly, a practical approach to managing sleep disorders in young men and women with JME is summarized. (International Journal of Biomedicine. 2018;8(2):108-114.)

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Section: Dosesupporting

confidence: 74%

Section: Psgmentioning

confidence: 91%

Section: Psgmentioning

confidence: 99%

Section: Psgmentioning

confidence: 99%

Section: The Epilepsy Itselfmentioning

confidence: 99%

See 3 more Smart Citations

Advances in the Management of Sleep Disorders in Juvenile Myoclonic Epilepsy

Moskaleva¹,

Шилкина²,

Shnayder³

et al. 2018

IJBM

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Sleep architecture in drug‐naïve adult patients with epilepsy: Comparison between focal and generalized epilepsy

et al. 2023

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Objective: Sleep impairment is one of the most common comorbidities affecting people with epilepsy (PWE). The bidirectional relation between epilepsy and sleep has been widely established. Several studies investigated subjective sleep quality and daytime vigilance in PWE, highlighting frequent complaints of sleep fragmentation, difficulties in falling asleep, and daytime sleepiness. The present study aimed to evaluate sleep structure in drug-naive PWE, distributed on the basis of epilepsy type, and compared with controls. Methods: This observational study included adult patients newly diagnosed with epilepsy and drug-naive as well as a control group of healthy subjects. All PWE and controls underwent a dynamic 24-h EEG with signals for sleep recording to evaluate sleep architecture, structure, continuity, and fragmentation.Results: Twenty-four PWE were included and distributed in two groups based on epilepsy type. Eleven patients were included in the generalized epilepsy group (63.6% male; 34.91 ± 9.80 years) and 13 patients in the focal epilepsy group (53.8% male; 38.69 ± 12.74 years). The control group included 16 subjects (56.3% male; 32.75 ± 12.19 years). Patients with generalized or focal epilepsy had a significantly lower sleep efficiency than controls. Moreover, both patient groups presented the alteration of markers of sleep fragmentation and loss of continuity, with higher indices of sleep stage transitions and arousal. Finally, the two patient groups presented less REM sleep than controls.

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