Advances in the Management of Sleep Disorders in Juvenile Myoclonic Epilepsy

Moskaleva, Polina; Шилкина, О. С.; Shnayder, N. А.; Artyukhov, Ivan; Дмитренко, Д. В.; Yuryeva, Elena

doi:10.21103/article8(2)_ra3

Cited by 2 publications

(1 citation statement)

References 38 publications

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“…They can also occur during relaxation periods later in the day. This feature of JME caused the figurative name "Cinderella syndrome" [36,37] (Fig. 3).…”

Section: Diagnostic Criteria For Juvenile Myoclonic Epilepsymentioning

confidence: 99%

Juvenile myoclonic epilepsy: current state of the problem

Shnayder

Petrov

2021

jour

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Due to the high prevalence of the disease, its genetic and clinical heterogeneity, the need for lifelong therapy and the emergence of new views on the pathogenesis and course of JME, it is necessary to provide primary care physicians (general practitioners, district therapists, neurologists) with up-to-date systematized information about the most common form of genetic generalized epilepsy (Herpin-Janz syndrome). JME is a genetically determined disease of the brain, accompanied by a triad of seizures (absences, myoclonia, generalized tonic-clonic seizures), and developing mainly in adolescence and young age. In recent years, monogenic and multifactorial forms of JME have been identified, but questions about the genetics of JME are far from being resolved. JME is characterized by the preservation of intelligence, life expectancy with adequate therapy does not differ from the average population, but the frequency of failures of pharmaco-induced remission is high when taking anticonvulsants is canceled. This explains the need for lifelong pharmacotherapy, individual selection of anticonvulsants. About 30% of patients with JME have non-psychotic mental disorders, disorders of the sleep and wake cycle, which in turn leads to an aggravation of epileptic seizures mainly in the first half of the day. This review presents an analysis of full-text publications in Russian and English over the past five years in the databases eLibrary, PubMed, Web of Science, OxfordPress, Springer, and Clinicalkeys. In addition, the review includes earlier publications of historical significance.

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“…They can also occur during relaxation periods later in the day. This feature of JME caused the figurative name "Cinderella syndrome" [36,37] (Fig. 3).…”

Section: Diagnostic Criteria For Juvenile Myoclonic Epilepsymentioning

confidence: 99%

Juvenile myoclonic epilepsy: current state of the problem

Shnayder

Petrov

2021

jour

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Exogenous melatonin as a disease-modifying therapy for epilepsy

Moskaleva

Shnayder

Незнанов

et al. 2019

Èpilepsiâ paroksizmalʹnye sostoâ.

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Резюме Использование мелатонина, как наиболее широко известного регулятора ритмов сна и бодрствования, в настоящее время вызывает большой интерес в отношении болезнь-модифицирующей терапии эпилепсии, так как одним из основных триггеров развития эпилептических припадков при некоторых формах эпилепсии является нарушение циркадианного ритма, при других-припадки развиваются из поверхностной фазы сна. Цельанализ исследований эффективности и безопасности применения экзогенного мелатонина как дополнительного лекарственного средства в рамках болезнь-модифицирующей терапии эпилепсии у детей и взрослых.

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Advances in the Management of Sleep Disorders in Juvenile Myoclonic Epilepsy

Cited by 2 publications

References 38 publications

Juvenile myoclonic epilepsy: current state of the problem

Juvenile myoclonic epilepsy: current state of the problem

Exogenous melatonin as a disease-modifying therapy for epilepsy

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