Skincare Bootcamp: The Evolving Role of Skincare

Rodan, Katie; Fields, Kathy; Majewski, George; Falla, Timothy J.

doi:10.1097/gox.0000000000001152

“…Nonetheless, the skin, primarily performing a barrier function, is constantly exposed to several exogenous factors such as pathogens and toxins which often impair its overall function [ 3 , 159 ]. Cosmetic and personal care products are therefore formulated to provide nutrients and protection to the skin, improve barrier functions, inhibit the growth of pathogens, and moisturize skin surfaces [ 9 , 10 ]. In this review, we have discussed the promising features of microbial biosurfactants in relation to their potential to enhance cosmetic and personal care products to performing these functions, should they be used in their formulations.…”

Section: Discussionmentioning

confidence: 99%

“…Moisturizing, protection, cleansing and prevention are the essential requirements for effective cosmetic and personal care products [ 10 ]. It must be pointed out that biosurfactants will only be used as substitutes for chemical surfactants in cosmetic and personal care products if they are able to deliver equal or better performance in their formulations and have a market price that makes them attractive.…”

Section: Challenges and Solutions For Biosurfactant Applicationsmentioning

confidence: 99%

“…Cosmetic and personal care products are often formulated to provide nutrients and protection to the skin, its flora and associated cells, in addition to improving barrier functions, inhibiting the growth of pathogens, cleansing and moisturizing skin surfaces, all of which improve the skin’s overall health. In pursuit of the above, researchers and manufacturers of personal skincare products have been actively investigating new and promising ingredients to add to their formulations [ 9 , 10 , 11 ]. At present, many manufacturers of personal skincare products use chemical surfactants as ingredients in their formulations, particularly as emulsifiers and foaming agents.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Microbial Biosurfactants in Cosmetic and Personal Skincare Pharmaceutical Formulations

Adu

¹

,

Naughton

²

,

Marchant

³

et al. 2020

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Cosmetic and personal care products are globally used and often applied directly on the human skin. According to a recent survey in Europe, the market value of cosmetic and personal care products in Western Europe reached about 84 billion euros in 2018 and are predicted to increase by approximately 6% by the end of 2020. With these significant sums of money spent annually on cosmetic and personal care products, along with chemical surfactants being the main ingredient in a number of their formulations, of which many have been reported to have the potential to cause detrimental effects such as allergic reactions and skin irritations to the human skin; hence, the need for the replacement of chemical surfactants with other compounds that would have less or no negative effects on skin health. Biosurfactants (surfactants of biological origin) have exhibited great potential such as lower toxicity, skin compatibility, protection and surface moisturizing effects which are key components for an effective skincare routine. This review discusses the antimicrobial, skin surface moisturizing and low toxicity properties of glycolipid and lipopeptide biosurfactants which could make them suitable substitutes for chemical surfactants in current cosmetic and personal skincare pharmaceutical formulations. Finally, we discuss some challenges and possible solutions for biosurfactant applications.

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“…Oil in water formulations tend to be lightweight gels, lotions, and serums and are best suited for normal to dry skin. Water in oil formulations may be ointments or creams and offer superior hydration for dry skin [80] B. Correct Sun-Protection: Singer et.al, 2019 reported that avoidance of sun exposure at peak times and textile sun protection are important pillars of a modern prophylactic approach.…”

Section: Skin Aging Prevention and Therapymentioning

confidence: 99%

Skin Aging & Modern Age Anti-aging Strategies

Mohiuddin¹

2019

GJMR

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As the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied with phenotypic changes in cutaneous cells as well as structural and functional changes in extracellular matrix components such as collagens and elastin. With intrinsic aging, structural changes occur in the skin as a natural consequence of the biological changes over time and produce a certain number of histological, physiological, and biochemical modifications. Intrinsic aging is determined genetically (influence of gender and ethnic group), variable in function of skin site, and also influenced by hormonal changes. Visually it is characterized by fine wrinkles. By comparison, “photoaging” is the term used to describe the changes occurring in the skin, resulting from repetitive exposure to sunlight. The histological, physiological, and biochemical changes in the different layers of the skin are much more drastic. From a mechanical point of view, human skin appears as a layered composite containing the stiff thin cover layer presented by the stratum corneum, below which are the more compliant layers of viable epidermis and dermis and further below the much more compliant adjacent layer of subcutaneous white adipose tissue.

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“…Oil in water formulations tend to be lightweight gels, lotions, and serums and are best suited for normal to dry skin. Water in oil formulations may be ointments or creams and offer superior hydration for dry skin [80].…”

Section: Cosmetological Carementioning

confidence: 99%

Skin Aging & Modern Age Anti-Aging Strategies

AK¹

2019

IJCDR

0

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As the most voluminous organ of the body that is exposed to the outer environment, the skin suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features such as wrinkling, loss of elasticity, laxity, and rough-textured appearance. This aging process is accompanied with phenotypic changes in cutaneous cells as well as structural and functional changes in extracellular matrix components such as collagens and elastin. With intrinsic aging, structural changes occur in the skin as a natural consequence of the biological changes over time and produce a certain number of histological, physiological, and biochemical modifications. Intrinsic aging is determined genetically (influence of gender and ethnic group), variable in function of skin site, and also influenced by hormonal changes. Visually it is characterized by fine wrinkles. By comparison, "photoaging" is the term used to describe the changes occurring in the skin, resulting from repetitive exposure to sunlight. The histological, physiological, and biochemical changes in the different layers of the skin are much more drastic. From a mechanical point of view, human skin appears as a layered composite containing the stiff thin cover layer presented by the stratum corneum, below which are the more compliant layers of viable epidermis and dermis and further below the much more compliant adjacent layer of subcutaneous white adipose tissue. Upon exposure to a strain, such a multi-layer system demonstrates structural instabilities in its stiffer layers, which in its simplest form is the wrinkling. These instabilities appear hierarchically when the mechanical strain in the skin exceeds some critical values. Their appearance is mainly dependent on the mismatch in mechanical properties between adjacent skin layers or between the skin and subcutaneous white adipose tissue, on the adhesive strength and thickness ratios between the layers, on their bending and tensile stiffness as well as on the value of the stress existing in single layers. Gradual reduction of elastic fibers in aging significantly reduces the skin's ability to bend, prompting an up to 4-fold reduction of its stability against wrinkling, thereby explaining the role of these fibers in skin aging. Anti-aging medicine is practiced by physicians, scientists, and researchers dedicated to the belief that the process of physical aging in humans can be slowed, stopped, or even reversed through existing medical and scientific interventions. This specialty of medicine is based on the very early detection and prevention of age-related diseases. Physicians practicing anti-aging medicine seek to enhance the quality of life as well as its length, limiting the period of illness and disability toward the end of one's life. Anti-aging medicine encompasses lifestyle changes (diet and exercise); hormone replacement therapies, as needed, determined by a physician through blood testing (DHEA, melatonin, thyroid, human growth hormone, estrogen, testosterone); antioxidants and vitamin supplements...

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Skincare Bootcamp: The Evolving Role of Skincare

Cited by 26 publications

References 36 publications

Microbial Biosurfactants in Cosmetic and Personal Skincare Pharmaceutical Formulations

Microbial Biosurfactants in Cosmetic and Personal Skincare Pharmaceutical Formulations

Skin Aging & Modern Age Anti-aging Strategies

Skin Aging & Modern Age Anti-Aging Strategies

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