Skin Tolerance of a New Bath Oil Containing St. John’s Wort Extract

Reuter, Juliane; Huyke, Constance; Scheuvens, H.; Ploch, M.; Neumann, Katrin; Jakob, Thilo; Schempp, C. M.

doi:10.1159/000148223

Cited by 17 publications

(10 citation statements)

References 48 publications

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“…In an irritation test, 50 μL per test area of a bath oil containing SJW extract was administered to the volar surface of the arm in 18 volunteers under occlusion for 24 h. After an hour, the test areas were evaluated; the test substance was readministered for another 24 h, and the skin areas were evaluated again for transepidermal water loss (TEWL), photometric measurements of skin erythema, and visual scoring. The bath oil did not cause irritation and was similar to the control of distilled water [97]. Topical application of SJW oil (with 110 μg/mL hypericin) or SJW ointment (30 μg/mL) on the forearms of volunteers and solar simulated radiation resulted in no or only mild photosensitization, respectively [16].…”

Section: Safety and Tolerability Of Dermal Applicationmentioning

confidence: 97%

Topical Application of St. Johnʼs Wort (Hypericum perforatum)

Seelinger²,

2013

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St. John's wort (Hypericum perforatum) has been intensively investigated for its antidepressive activity, but dermatological applications also have a long tradition. Topical St. John's wort preparations such as oils or tinctures are used for the treatment of minor wounds and burns, sunburns, abrasions, bruises, contusions, ulcers, myalgia, and many others. Pharmacological research supports the use in these fields. Of the constituents, naphthodianthrones (e.g., hypericin) and phloroglucinols (e.g., hyperforin) have interesting pharmacological profiles, including antioxidant, anti-inflammatory, anticancer, and antimicrobial activities. In addition, hyperforin stimulates growth and differentiation of keratinocytes, and hypericin is a photosensitizer which can be used for selective treatment of nonmelanoma skin cancer. However, clinical research in this field is still scarce. Recently, sporadic trials have been conducted in wound healing, atopic dermatitis, psoriasis, and herpes simplex infections, partly with purified single constituents and modern dermatological formulations. St. John's wort also has a potential for use in medical skin care. Composition and stability of pharmaceutical formulations vary greatly depending on origin of the plant material, production method, lipophilicity of solvents, and storage conditions, and this must be regarded with respect to practical as well as scientific purposes.

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Section: Safety and Tolerability Of Dermal Applicationmentioning

confidence: 97%

Topical Application of St. Johnʼs Wort (Hypericum perforatum)

Seelinger²,

2013

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“…Skin care products with a high lipid content are recommended for the care of dry skin and inflammatory skin conditions . Pure oils, as well as oils integrated in diverse formulations are frequently applied for skin care being known for their capacity to moisturize the skin by supporting the native lipids of the stratum corneum to provide a better barrier function .…”

mentioning

confidence: 99%

In vivo investigations on the penetration of various oils and their influence on the skin barrier

Patzelt

Lademann

Richter

et al. 2011

Skin Research and Technology

121

128

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“…It is used in premenstrual syndrome, placebo, placebocontrolled trial, remedy for wounds, and muscle pain 36 .…”

Section: Hypericum Perforatum/ Hypericaceaementioning

confidence: 99%

Untitled

2013

IJPSR

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This article addresses the basic concepts of herbal technology which is used worldwide. 21 st century is the century of Biology mechanical and propelled by scientific knowledge and hi-tech expertise. Herbal technology, are going to be the most influential elements that are fundamental for success and welfare for the people of nations. Information on the herbal technology was collected via electronic search (using pub med, scifinder, Google Scholar and web of science) and library search for articles published in peer-reviewed journals. Furthermore, information also was obtained from some local books on ethnopharmacology. Nutraceutical are food or part of the food that grant medical or health benefits together with the prevention or cure of the disease. Cosmaceuticals are the largest accumulation to the health trade and are described as cosmetic products with drug; they are the fastest increased segment in the skin care market. Biopesticides are cost effective, safer, readily available, and ecological and therefore more environment-friendly and will offer substitute to conventional pesticides. Herbal drugs represent a major contribute to all the formally recognized systems of health in India. An upward trend has been experimental in the research on herbals. Export-Import reports reveal that the global trade of herbal technology and plant originated products is around US $250 billion. In the present article, an attempt has been made to present an overview of the herbal technology in the international market and intends to throw in the knowledge about Herbal drugs, Nutraceuticals, Cosmaceuticals, and Biopesticides which comes under herbal technology.

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Skin Tolerance of a New Bath Oil Containing St. John’s Wort Extract

Cited by 17 publications

References 48 publications

Topical Application of St. Johnʼs Wort (Hypericum perforatum)

Topical Application of St. Johnʼs Wort (Hypericum perforatum)

In vivo investigations on the penetration of various oils and their influence on the skin barrier

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