Skin Surface Topography and Texture Analysis of Sun-Exposed Body Sites in View of Sunscreen Application

Korn, Verena; Surber, Christian; Imanidis, Georgios

doi:10.1159/000450760

Cited by 20 publications

(16 citation statements)

References 30 publications

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“…The presented RCM images showed the skin before and after the application of the formulations and only illustrate the morphological qualitative analysis. An increase of brightness on skin surface can be related to an improvement of skin surface texture by film formation .…”

Section: Resultsmentioning

confidence: 99%

Application of biophysical and skin imaging techniques to evaluate the film‐forming effect of cosmetic formulations

Melo¹,

Campos²

2019

Intern J of Cosmetic Sci

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OBJECTIVE: Products with film-forming effect, or 'second skin', which guarantees an immediate protective effect after application, is a highlight, especially when composed of natural ingredients. Thus, the objective of this study was to evaluate the immediate film-forming effect on skin of a gel and emulsion formulations added with Kappaphycus alvarezii and Caesalpinia spinosa extracts through biophysical and skin imaging techniques, especially with the Reflectance Confocal Microscopy (RCM). METHODS: The measurements were done in the forearm region before (baseline) and 1 h after of application of the developed formulation and its control. The parameters related to the stratum corneum water content, transepidermal water loss (TEWL), cutaneous microrelief and morphological and structural characteristics of the epidermis were analysed through the following biophysical and skin imaging techniques: Corneometer â CM 825, Tewameter â TM 300, Visioscan â VC98 and Vivascope â 1500, respectively. A sensorial analysis was also performed to study how the formulations were perceived on the skin. RESULTS: The obtained results showed that the active ingredient under study allows the film formation on the skin surface, leading to a reduction of TEWL and skin desquamation. The obtained

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Section: Resultsmentioning

confidence: 99%

Application of biophysical and skin imaging techniques to evaluate the film‐forming effect of cosmetic formulations

Melo¹,

Campos²

2019

Intern J of Cosmetic Sci

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“…Other interesting studies have also been performed on skin replicas, measuring indirectly the 3D profile characteristics of the skin. Korn et al [ 66 ] have evaluated how sun exposure affects skin roughness by measuring negative imprints of the skin surface obtained using a two-component silicone rubber and catalyst system. The replicas were measured by means of a commercial 3D optical profilometer.…”

Section: Three-dimensional Topographymentioning

confidence: 99%

Optical Technologies for the Improvement of Skin Cancer Diagnosis: A Review

Rey-Barroso

Peña-Gutiérrez

Yáñez

et al. 2021

Sensors

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The worldwide incidence of skin cancer has risen rapidly in the last decades, becoming one in three cancers nowadays. Currently, a person has a 4% chance of developing melanoma, the most aggressive form of skin cancer, which causes the greatest number of deaths. In the context of increasing incidence and mortality, skin cancer bears a heavy health and economic burden. Nevertheless, the 5-year survival rate for people with skin cancer significantly improves if the disease is detected and treated early. Accordingly, large research efforts have been devoted to achieve early detection and better understanding of the disease, with the aim of reversing the progressive trend of rising incidence and mortality, especially regarding melanoma. This paper reviews a variety of the optical modalities that have been used in the last years in order to improve non-invasive diagnosis of skin cancer, including confocal microscopy, multispectral imaging, three-dimensional topography, optical coherence tomography, polarimetry, self-mixing interferometry, and machine learning algorithms. The basics of each of these technologies together with the most relevant achievements obtained are described, as well as some of the obstacles still to be resolved and milestones to be met.

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“…The biological variation of human skin characteristics, such as skin surface topography, may differentially alter the effectiveness of applied sunscreen films [5,20–26]. Furthermore, sweating can alter skin conditions, such as skin surface pH and hydration of the stratum corneum, or even reduce the tolerance of unprotected skin to sunburn [27–30].…”

Section: Introductionmentioning

confidence: 99%

In vitro skin model for characterization of sunscreen substantivity upon perspiration

Keshavarzi

Knudsen

Brewer

et al. 2021

Intern J of Cosmetic Sci

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Objective The resistance of sunscreens to the loss of ultraviolet (UV) protection upon perspiration is important for their practical efficacy. However, this topic is largely overlooked in evaluations of sunscreen substantivity due to the relatively few well‐established protocols compared to those for water resistance and mechanical wear. Methods In an attempt to achieve a better fundamental understanding of sunscreen behaviour in response to sweat exposure, we have developed a perspiring skin simulator, containing a substrate surface that mimics sweating human skin. Using this perspiring skin simulator, we evaluated sunscreen performance upon perspiration by in vitro sun protection factor (SPF) measurements, optical microscopy, ultraviolet (UV) reflectance imaging and coherent anti‐Stokes Raman scattering (CARS) microscopy. Results and conclusion Results indicated that perspiration reduced sunscreen efficiency through two mechanisms, namely sunscreen wash‐off (impairing the film thickness) and sunscreen redistribution (impairing the film uniformity). Further, we investigated how the sweat rate affected these mechanisms and how sunscreen application dose influenced UV protection upon perspiration. As expected, higher sweat rates led to a large loss of UV protection, while a larger application dose led to larger amounts of sunscreen being washed‐off and redistributed but also provided higher UV protection before and after sweating.

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Skin Surface Topography and Texture Analysis of Sun-Exposed Body Sites in View of Sunscreen Application

Cited by 20 publications

References 30 publications

Application of biophysical and skin imaging techniques to evaluate the film‐forming effect of cosmetic formulations

Application of biophysical and skin imaging techniques to evaluate the film‐forming effect of cosmetic formulations

Optical Technologies for the Improvement of Skin Cancer Diagnosis: A Review

In vitro skin model for characterization of sunscreen substantivity upon perspiration

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