Skin Microcirculatory Organization Types in Arterial Hypertension by the Data of Doppler Flowmetry

Васильев, А. П.; Streltsova, N. N.; Секисова, М. А.

doi:10.15829/1560-4071-2015-4-7-12

Cited by 3 publications

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References 2 publications

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“…(22) Omega-3 telah digunakan sebagai terapi tambahan seperti penelitian yang dilakukan di Rusia terhadap 22 pasien dengan hipertensi dan sindroma metabolik yang diberikan 1,5 gram omega 3 selama 1 bulan dapat menurunkan tekanan darah pasien hipertensi. (23) Mori TA menyatakan bahwa efek kardio protektif omega-3 berhubungan dengan perbaikan tekanan darah, fungsi jantung, tahanan arteri dan fungsi vaskuler. Mori TA menyatakan bahwa EPA dan DHA mempunyai peranan yang berbeda.…”

Section: Konsumsi Asam Lemak Omega-3 (Ala Epa Dha) Subjek Penelitianunclassified

Hubungan Asupan Dan Kadar Omega-3 Plasma Dengan Kejadian Hipertensi Pada Etnik Minangkabau Di Kota Padang

Sulastri¹

2015

MKA

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AbstrakHipertensi merupakan masalah kesehatan utama di Indonesia maupun di dunia Hampir 95% kasus hipertensi tidak diketahui penyebabnya atau disebut hipertensi esensial (HET). Pola konsumsi yang baik dan seimbang merupakan salah satu upaya pengendalikan tekanan darah. Omega-3 adalah salah satu zat gizi yang dapat menurunkan tekanan darah. Omega-3, terbukti berperan dalam mencegah beberapa penyakit kronis termasuk hipertensi. Telah dilakukan penelitian dengan desain cross sectional study untuk melihat hubungan omega-3 plasma dengan kejadian hipertensi. Penelitian dilakukan pada 130 orang yang terdiridari subjek hipertensi dan normotensi. Pengambilan sampel dengan cara sistematik random sampling dengan memperhatikan kriteria inklusi dan ekslusi. Asupan omega-3 dihitung menggunakan FFQ dan kadar omega-3 plasma diukur dengan teknik methylasi. Hasil penelitian ini adalah asupan omega-3 adalah 0,66±0,61 gram/hari, EPA 0,29 ± 0,23 gram/hari, DHA (22:6) 0,85± 0,65 gram/hari dan kelompok normotensi ALA 0,64± 0,55 gram/hari, EPA 0,27±0,15 gram/hari, DHA 21,34 ± 174,14 gram/hari. Tidak terdapat perbedaan bermakna asupan omega-3 dengan kadar omega-3 plasma antara kelompok hipertensi dengan kelompok normotensi dan tidak terdapat hubungan yang bermakna antara asupan omega-3 dan kadar omega-3 plasma dengan kejadian hipertensi. Hasil penelitian ini tidak mendukung hubungan antara omega-3 dengan kejadian hipertensi Kata kunci : hipertensi, omega-3, EPA, ALA, DHA AbstractHypertension is the leading health problem in the community in Indonesia and even in certain countries all over the world. Almost 95% of hypertension cases are from unknown cause which is also known as essential hypertension (HET). Planned and balanced consumption pole is one of the efforts to control blood pressure. Omega-3 is one of the nutrients that reduce blood pressure. Omega-3 is proven to involve in preventing certain chronic disease including hypertension. A cross-sectional study carried out to identify the correlation between Omega-3 plasma and the hypertension incidence. 130 subjects were selected and divided ARTIKEL PENELITIAN

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Section: Konsumsi Asam Lemak Omega-3 (Ala Epa Dha) Subjek Penelitianunclassified

Hubungan Asupan Dan Kadar Omega-3 Plasma Dengan Kejadian Hipertensi Pada Etnik Minangkabau Di Kota Padang

Sulastri¹

2015

MKA

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Skin microcirculation in patients with heart failure with different left ventricular systolic dysfunction

Подзолков

Dragomiretskaya

Beliaev

et al. 2021

Cardiovasc Ther Prev

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Aim. To study the relationship of mechanisms of microcirculation regulation and intracardiac hemodynamics in patients with heart failure (HF).Material and methods. In eighty patients with NYHA class II-IV HF, microcirculation was assessed by laser Doppler flowmetry and intracardiac hemodynamics — by echocardiography.Results. The patients were divided into 3 groups depending on HF type: with preserved ejection fraction (CHpEF) (>50%) — 27 patients, mid-range EF (CHmrEF) (40-50%) — 25 patients, reduced EF (CHrEF) (<40%) — 28 patients. Comparative analysis revealed a significant decrease in the coefficient of variation (CV) in all groups without microcirculation differences. The greatest number of significant correlations was found between the myogenic component of microcirculation frequency range and the following echocardiographic parameters: left ventricular EF (r=0,351, p<0,05); end-diastolic dimension (r=-0,492, p<0,05), end-systolic dimension (r=-0,474, p<0,05), end-diastolic volume (r=-0,544, p<0,05), end-systolic volume (r=-0,449, p<0,05), etc.Conclusion. In patients, regardless of left ventricular EF, satisfactory perfusion was obtained, which is achieved due to inhibition of active mechanisms and compensatory activation of passive mechanisms of microcirculation regulation. The relationship between the development of myocardial remodeling and microcirculatory dysfunction is noted.

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The influence of smoking on the functional state of microcirculation according to laser doppler flowmetry and clinical anamnestic data of patients with arterial hypertension

Streltsova

Vasilyev

2021

Lazernaâ medicina

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Background. Detailed study of the functional state of microcirculation in combination of arterial hypertension and tobacco smoking, as the most common and prognostically important risk factors for atherogenesis, will not only clarify pathogenetic effect of tobacco smoke on the terminal vascular bed, but also outline directions of active counteraction to it.Purpose. To study the effect of TS on the functional state of SM using laser Doppler flowmetry in patients with AH.Methods. 185 patients with stage 1,2 AH involved in the study were divided into 2 equivalent groups according to main clinical and laboratory data: group 1 – non-smokers (n = 134, mean age was 57.0 [50.0; 60.0]), group 2 – patients who smoke 1–1.5 packs of cigarettes per day (n = 51, mean age was 54.0 [48.0; 58.0]). Patients were prescribed short-acting antihypertensives drugs, which were used whenever required 5 days before the study. SM was investigated by laser Doppler flowmetry using occlusion test and amplitude-frequency spectrum analysis of hemoperfusion fluctuations.Results. Obtained data showed negative acute effect of ingredients of tobacco smoke on almost all structural elements of microhemocirculation. Revealed deviations are characterized by constriction of precapillary segment of microvascular bed with increase in myogenic tone and equal 3.1 units [2.6; 4.1] versus 2.3 units [1.7; 3.4] in the alternative group (p = 0.007), decrease in capillary blood flow from 4.5 units [3.5; 5.8] compared with the group of non-smokers – 5.2 units [4.0; 7.3] (p = 0.041), statistically significant intensification of arteriolar-venular blood flow with formation of venous congestion, limitation of dilated reserve of microcirculation.Conclusion. Tobacco smoking leads to significant microcirculation disorders that are projected onto changes in terminal vascular bed, inherent with AH, which significantly reduces the functional state of microcirculation, limits its reserve potential and promotes the development of tissue ischemia.

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Skin Microcirculatory Organization Types in Arterial Hypertension by the Data of Doppler Flowmetry

Cited by 3 publications

References 2 publications

Hubungan Asupan Dan Kadar Omega-3 Plasma Dengan Kejadian Hipertensi Pada Etnik Minangkabau Di Kota Padang

Hubungan Asupan Dan Kadar Omega-3 Plasma Dengan Kejadian Hipertensi Pada Etnik Minangkabau Di Kota Padang

Skin microcirculation in patients with heart failure with different left ventricular systolic dysfunction

The influence of smoking on the functional state of microcirculation according to laser doppler flowmetry and clinical anamnestic data of patients with arterial hypertension

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