Skin manifestations in end stage renal disease patients on hemodialysis.

Abstract

Chronic kidney disease (CKD) is a world public health problem that is related with high morbidity and mortality. CKD patients can present with different skin manifestations, often benign with much impact on quality of patients life. Study Design: Case-series study. Setting: Nephrology Unit Civil Hospital Larkana. Period: From 1st January 2018 to 30th June 2018. Material and methods: 141 patients of ESRD on regular HD for at least 1 month. Patients were chosen randomly for evaluation of cutaneous changes regardless of their gender, age, sex and etiology of ESRD. General and dermatological examination of the skin, hair, nails, and oral mucosa was performed by consultant dermatologist. Data were analyzed by using IBM SPSS version 23.0. Descriptive analyses performed using mean with standard deviation and median with inter quartile ranges of quantitative data set. Count and percentages were reported for categorical data set. Results: In the present study there were one hundred and forty one patients. Out of them skin manifestations of patients, 87.9% had Xerosis, 31.9% found with skin hyper pigmentation, 9.2% had Subungal Hyperkeratosis, 24.1% had Uremic Pruirtis, 45.4% had Pallor, and 6.4% found with Bruises. There were 9.9% cases of Alopecia, 17.7% cases of half n half nail, 1.4% cases of half n half nail with alopecia, 9.2% cases of Koilionychia, 0.7% cases of Koilionychia with alopecia, 2.8% found with koilonychias and half n half nail, 2.1% with leuconycia and koilionychia, 15.5% with Leuconychia, 2.1% found with Leuconychia and alopecia, and 0.7% found with Leuconychia, koilonychia & alopecia in Hair and Nail changes. Conclusion: The range of skin manifestations vary in different studies. Although often benign with much impact on quality of patient’s life and life can be threatening. Early treatment of skin disorders can improve the quality of life.

Avaliação das manifestações dermatológicas em pacientes com doença renal crônica em um serviço de hemodiálise no Distrito Federal

“…Seu tratamento consiste em hidratação diária da pele com cremes contendo de 5 a 10% de ureia (Goel et al, 2021), bem como limitar as lavagens de mãos e os banhos e evitar agentes que causem irritação cutânea (Blaha et al, 2018). Na análise de dados, observa-se que a xerose estava presente em 83,3% dos pacientes, sendo a manifestação cutânea mais encontrada, indo de encontro à literatura, que mostra frequência igualmente elevada de 87,9% (Shaikh et al, 2019). Essa alteração também foi a mais observada por Udayakumar el at.…”

“…É caracterizada pela redução no número e na funcionalidade dos néfrons, por mais de 3 meses, de forma progressiva e irreversível, sendo determinada pela taxa de filtração glomerular (TFG). Conforme a redução desta, a DRC é classificada em 5 estágios, sendo a doença renal crônica terminal (DRCT) o último estágio (Shaikh et al, 2019). Segundo a National Kidney Foundation (2015), a DRCT é definida como TFG < 15 ml/min/1.73 m².…”

Manifestasi dermatologik pada pasien gagal ginjal kronis

“…1 GGK dibagi menjadi 5 stadium berdasarkan laju filtrasinya, yaitu stadium 1 dengan LFG normal, stadium 2 dengan LFG 60-90ml/menit, stadium 3 dengan LFG 30-60ml/menit, stadium 4 dengan 15-30 ml/menit, dan stadium 5 dengan LFG <15 ml/menit yang disebut dengan gagal ginjal terminal (GGT). 2 Gagal ginjal kronis memiliki tingkat morbiditas dan mortalitas yang cukup tinggi di dunia.…”

A Scoping Review: Factors Associated with Pruritus in CKD (Chronic Kidney Disease) Patients Undergoing Dialysis

“…Pruritus is a skin problem that interferes with the quality of sleep and daily activities of patients with chronic kidney failure due to the itchiness that appears (Shaikh et al, 2019). Not only that, Juanda research (2017) states that pruritus gives patients a feeling of discomfort, embarrassment, and lack of confidence.…”