Skin erythema and pigmentation: a review of optical assessment techniques

Abdlaty, Ramy; Hayward, Joseph E.; Farrell, Thomas J.; Fang, Qiyin

doi:10.1016/j.pdpdt.2020.102127

Cited by 24 publications

(20 citation statements)

References 95 publications

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“…Technology offers a few solutions for eliminating subjectivity and quantifying skin erythema and hyperpigmentation, such as spectra-based assessment or imaging-based assessment. 6 Narrow-band reflectance spectrophotometry (NBRS) was used to determine skin colour, both erythematous and hyperpigmented skin lesions, but so far this method has not been used in LoS. 7–14 …”

Section: Introductionmentioning

confidence: 99%

Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study

Szczepanek

Frątczak

Lis‐Święty

2021

CCID

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Background Localized scleroderma (LoS) is an inflammatory fibrosing disease of the connective tissue, whose esthetic sequelae are atrophic skin lesions with hyperpigmentation. The key element of diagnostic and therapeutic procedures is the assessment of the disease's severity and damage. The study objective was to analyze the usefulness of narrow-band reflectance spectrophotometry (NBRS) to assess erythema and hyperpigmentation in LoS lesions. Materials and Methods Erythema indexes (EI) and melanin indexes (MI) were determined with the use of DermaLab Combo skin colour probe for LoS lesions and symmetrically located areas of normal skin. Then, relative percentage differences were determined for EI and MI, which were compared with the visual assessments of erythema and hyperpigmentation according to the Localized Scleroderma Cutaneous Assessment Tool (LoSCAT). Results A total of 84 LoS lesions were studied in 41 patients. The study showed a moderate correlations between the spectrophotometric measurements and clinical assessments of erythema as well as hyperpigmentation (Spearman correlation coefficient, r), r = 0.37; p = 0.00047 and r = 0.55; p=0.0000001, respectively. Conclusion NBRS seems to be a useful tool to assess the severity of erythema and hyperpigmentation in LoS lesions. Further studies are required in order to compare the spectrophotometric results with other objective methods.

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Section: Introductionmentioning

confidence: 99%

Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study

Szczepanek

Frątczak

Lis‐Święty

2021

CCID

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“…However, even on such unified conditions, the internal consistency of the grading results was not satisfying. In clinical practice, the evaluation by a doctor could be subject to a variety of factors apart from unstandardized evaluating standards, such as different illuminations, varied clinical experience, and other subjective factors, and the feedback of the patient 21 . Therefore, the introduction of imaging techniques does provide a reference value that could guide clinicians in determining individualized therapy or to monitor response.…”

Section: Discussionmentioning

confidence: 99%

Assessment of features in facial hyperpigmentation: Comparison study between VISIA and CSKIN

Zuo

et al. 2022

Skin Research and Technology

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Background: Hyperpigmentary disorder is one of the commonest skin concerns in dermatology clinics. The availability of noninvasive instruments provided a convenient, objective, and reproducible methodology for the evaluation of pigmentation and skin color. The aim of this study is to compare CSKIN and VISIA in measuring facial hyperpigmentation, as well as to assess the correlation between the instrumental analyzing and clinical evaluation. Methods: Eighty Chinese patients were enrolled. Images were taken and analyzed by VISIA from Canfield and CSKIN from Yanyun Technology, and the facial hyperpigmentation was graded by three dermatologists. Results: Feature counts within the facial pigmented areas analyzed by VISIA showed positive correlations with brown pixels (r = 0.331, p < 0.05) and brown percent (r = 0.395, p < 0.0001) measured by CSKIN. The parameters measured by CSKIN and VISIA were significantly correlated with visual scores graded by the dermatologists, with VISIA presenting a moderate correlation (r = 0.509, p < 0.001) and CSKIN a slightly stronger correlation with the visual scores (r = 0.653, p < 0.001). Conclusion: CSKIN could serve as an alternative in the assessment and follow-up of skin disease featuring with facial hyperpigmentation.

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“…The study of Nesa et al showed remarkable analgesic, anti-inflammatory, and central nervous system (CNS) depressant effects of henna [38]. Hasan Imam et al suggested that the analgesic effect of henna was resulted from alpha skin redness increased due to the use of henna ointment, which may be due to the method of measuring erythema [30].…”

Section: Efficacy Outcomesmentioning

confidence: 99%

Efficacy of a topical formulation of Henna (Lawsonia inermis) on the itch and wound healing in patients with epidermolysis bullosa: A pilot single-arm clinical trial

Niazi¹,

Parvizi²,

Saki³

et al. 2022

Dermatol Pract Concept

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Introduction: Epidermolysis bullosa (EB) is a rare inherited genetic skin disorder with severe skin itching and recurrent blisters and erosion. There is no effective and specific therapy for all types of EB. Objective: The aim of this study was to evaluate a topical formulation of henna (Lawsonia inermis L.) in the management of wounds and the itching sensation in patients with EB. Methods: This is a pilot single-arm clinical trial. Nine patients with recessive dystrophic EB (RDEB), with the age range of 5 to 32 years old were enrolled in the study. The patients were instructed to apply the topical 1% henna ointment once daily on two erosions and on also two sites with moderate to a severe itching sensation. The total duration of the intervention was four weeks with weekly follow-up visits. Patient global impression of improvement (PGI-I), visual analog scale (VAS), and clinical global impression of improvement (CGI-I) were used for assessing the wound healing process and itching discomfort. Results: There was a significant improvement in the skin symptoms of epidermolysis bullosa including skin redness, itching, burning, and local warmness (p-value<0.05). Local pain decreased during the study period, but this was not statistically significant (p-value<0. 0.19). One patient reported moderate xerosis of skin after continuous usage. Conclusion: It seems that the topical formulation of henna may be effective in the management of itching, burning, stringing, and cutaneous warmness sensation in patients with EB. Further controlled studies with larger sample sizes are recommended to better evaluate this formulation.

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Skin erythema and pigmentation: a review of optical assessment techniques

Cited by 24 publications

References 95 publications

Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study

Narrow-Band Reflectance Spectrophotometry for the Assessment of Erythematous and Hyperpigmented Skin Lesions in Localized Scleroderma: A Preliminary Study

Assessment of features in facial hyperpigmentation: Comparison study between VISIA and CSKIN

Efficacy of a topical formulation of Henna (Lawsonia inermis) on the itch and wound healing in patients with epidermolysis bullosa: A pilot single-arm clinical trial

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