“…In this connection, many papers are aimed at determining the concentration of free glucose in blood, interstitial fluid, and other fluids of the body [20][21][22][23][24][25][26][27][28][29][30], revealing the morphological changes in vital organs [10, 12, One third of all patients with diabetes mellitus have complications in the form of skin lesions, the most severe of them being the chronic ulcers that recover very slowly, thus increasing the risk of infection [19,[57][58][59]. Diabetes mellitus increases the risk of cardiovascular diseases, retinopathy that leads to blindness, neuropathy and nephropathy [8-13, 19, 31, 60-64].…”