Skin barrier immunology from early life to adulthood

Trompette, Aurélien; Ubags, Niki

doi:10.1016/j.mucimm.2023.02.005

Cited by 13 publications

(8 citation statements)

References 191 publications

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“…Due to the similarity between liposomes structure and skin cells, the liposomal bilayer merges with the cellular membrane's phospholipid bilayer at the SC, where the UV filters should remain retained for photoprotective action [69][70][71]. Moreover, due to the presence of phospholipids in both liposomes and the SC, this system presents a suitable biocompatibility with the skin, reducing irritation and allergic reactions [44,64].…”

Section: Liposomes As a Strategy For Ulraviolet Filter Deliverymentioning

confidence: 99%

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Miranda,

Cruz,

Girão

et al. 2024

Pharmaceutics

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Sunscreen products are essential for shielding the skin from ultraviolet (UV) radiation, a leading cause of skin cancer. While existing products serve this purpose, there is a growing need to enhance their efficacy while minimizing potential systemic absorption of UV filters and associated toxicological risks. Liposomal-based formulations have emerged as a promising approach to address these challenges and develop advanced photoprotective products. These vesicular systems offer versatility in carrying both hydrophilic and lipophilic UV filters, enabling the creation of broad-spectrum sunscreens. Moreover, their composition based on phospholipids, resembling that of the stratum corneum, facilitates adherence to the skin’s surface layers, thereby improving photoprotective efficacy. The research discussed in this review underscores the significant advantages of liposomes in photoprotection, including their ability to limit the systemic absorption of UV filters, enhance formulation stability, and augment photoprotective effects. However, despite these benefits, there remains a notable gap between the potential of liposomal systems and their utilization in sunscreen development. Consequently, this review emphasizes the importance of leveraging liposomes and related vesicular systems as innovative tools for crafting novel and more efficient photoprotective formulations.

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Section: Liposomes As a Strategy For Ulraviolet Filter Deliverymentioning

confidence: 99%

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Miranda,

Cruz,

Girão

et al. 2024

Pharmaceutics

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“…Thus, being the first line of defense of the immune system, its damage can affect human health. [ 152 ] The main skin protective activities of A. japonicus involve antimelanin, antiaging, antioxidative stress, antiwrinkle, and repair of the skin barrier.…”

Section: Biological Activity and Pharmacological Actionmentioning

confidence: 99%

Chemical substances and their activities in sea cucumber Apostichopus japonicus: A review

Lu,

Wang,

et al. 2023

Archiv der Pharmazie

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Apostichopus japonicus, also known as Stichopus japonicus, with medicinal and food homologous figures, is a globally recognized precious ingredient with extremely high nutritional value. There is no relevant review available through literature search, so this article selects the research articles through the keywords “sea cucumber” and “Apostichopus japonicus (Stichopus japonicus)” in six professional databases, such as Wiley, PubMed, ScienceDirect, ACS, Springer, and Web of Science, from 2000 to the present, summarizing the extraction, isolation, and purification methods for the four major categories (polysaccharides, proteins and peptides, saponins, and other components) of the A. japonicus chemical substances and 10 effective biological activities of A. japonicus. Included are anticoagulation, anticancer/antitumor activities, hematopoiesis, regulation of gut microbiota, and immune regulatory activities that correspond to traditional efficacy. Literature support is provided for the development of medicines and functional foods and related aspects that play a leading role in future directions.

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“…It may result from harmful actions acting on an organ or living tissue, causing deviations in its functions or due to physical injuries, or even trauma. The injury can be classified as acute or chronic, the primary distinctions between chronic and acute injuries are delineated through temporal duration and provenance/causality (Diniz et al, 2021;Trompette;Ubags, 2023). The newborn's skin qualifies as excellent in its delicacy and vulnerability.…”

Section: Introductionmentioning

confidence: 99%

Skin lesions associated with invasive devices in highly complex neonatal and pediatric patients

Ribeiro,

Oliveira,

Constantino

et al. 2024

Braz. J. of Sci.

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The skin is the largest organ of the human body. It has three layers: epidermis, dermis and hypodermis. The epidermis performs multiple functions in the body, standing out as a defensive barrier and internal integrity in addition to containing the evasion of moisture, and exogenous substances. Injury is by definition any interruption in the continuity of the skin regardless of its extent and may be chronic or acute. A newborn's skin is delicate and vulnerable, and the use of invasive devices in highly complex care can negatively affect its integrity. This review study addressed data from Brazilian research on newborn skin in intensive hospital treatment units. The studies evaluated were obtained from the SciELO, Medline and Lilacs, Google Scholar and Elsevier databases. The inclusion criteria were articles, monographs, dissertations and theses published in the period between 2018 and 2023, in Portuguese with a pre-established theme, and the exclusion criteria were articles, monographs, dissertations and repeated theses, incomplete manuscripts and with unauthorized access free of charge. As results, 3 categories were obtained: Category 1 – Main causes of skin lesions in newborns and highly complex children. Category 2- Prevention measures in newborns and highly complex children with skin lesions. Category 3- Highly complex skin care strategies for newborns and children. It is evident that due to the high susceptibility of newborns and children to develop highly complex skin lesions, it requires greater attention from the nursing team. Early detection of the risk of skin lesions and the use of prophylaxis enable a better quality of life for newborns hospitalized in high complexity, avoiding and minimizing skin lesions caused by the care provided.

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Skin barrier immunology from early life to adulthood

Cited by 13 publications

References 191 publications

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Beyond Traditional Sunscreens: A Review of Liposomal-Based Systems for Photoprotection

Chemical substances and their activities in sea cucumber Apostichopus japonicus: A review

Skin lesions associated with invasive devices in highly complex neonatal and pediatric patients

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