Skin and mucosal manifestations in vitamin deficiency

Barthélémy, H.; Chouvet, B; Cambazard, F.

doi:10.1016/s0190-9622(86)70301-0

Cited by 50 publications

(16 citation statements)

References 26 publications

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“…This is the first reported case of such an association in the literature. In contrast, aphthous ulcers of the oral cavity, as in our patient, are not uncommon in vitamin B12 deficiency 4,5 …”

contrasting

confidence: 52%

Livedo reticularis associated with pernicious anaemia

Sevastos

Rafailidis

Katoulis

et al. 2003

Clinical and Experimental Dermatology

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contrasting

confidence: 52%

Livedo reticularis associated with pernicious anaemia

Sevastos

Rafailidis

Katoulis

et al. 2003

Clinical and Experimental Dermatology

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“…Niacin deficiency remains a clinical diagnosis, by recognition of the symptoms and therapeutic trial of supplementation. 25 As Harris wrote in 1941, ''Men's opinions may change but facts remain the same always . .…”

Section: Recognition and Treatment Of Modern Pellagramentioning

confidence: 99%

Pharmacologic Use of Niacin

Prousky

Millman²,

Kirkland

2011

J Evid Based Complementary Altern Med

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Niacin is required for a host of critical redox and adenosine diphosphate-ribosylation reactions in metabolism. Niacin deficiency leads to the distinctive signs and symptoms of pellagra, but these can happen in an unpredictable progression and can be altered in patients with polymorphisms in any of the hundreds of niacin-dependent enzymes. The symptomatology of niacin deficiency is becoming a forgotten knowledge base, and niacin deficiency is likely underdiagnosed. Additionally, high levels of niacin and niacinamide have pharmacological effects distinct from their role as sources of vitamin B3, allowing a wide range of effects on processes such as blood flow and lipid metabolism, which can be used to treat or prevent a variety of disease processes.

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“…As previously mentioned, one frequently stated theory is that no diet-induced deficiency of vitamin K exists in humans. '• 16 This belief is clearly incorrect. As far back as 1939, a group of patients who had diets deficient in fruits and vegetables or who ate irregularly were described as having prolongation of the prothrombin time, which responded to oral administration of vitamin K. 17 Thus, the investigators concluded that these patients had vitamin K deficiency because none had liver disease or biliary obstruction.…”

Section: (Mayo Clin Proc 1994; 69:462-466)mentioning

confidence: 99%