Skin and Lacrimal Drainage System

Yanoff, Myron; Sassani, Joseph W.

doi:10.1016/b978-0-323-54755-0.00006-1

Cited by 3 publications

(4 citation statements)

References 374 publications

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“…Metastasis was found in a few reported cases (1–22%). It is difficult to distinguish between chronic dacryocystitis and lacrimal sac mucocele [3-5, 17, 26-36, 38]. The sac patency test revealed an obstruction in the LDS of this case series.…”

Section: Discussionmentioning

confidence: 75%

“…The recurrence rate of invasive epithelial malignancies (squamous cell, mucus-secreting adenocarcinoma, and nonkeratinizing SqCC) appears to be approximately 50%, and mortality is 37–100% with treatment for nonkeratinizing SqCC [3-5, 36, 38, 40, 47, 52]. Metastasis to the bone and skin has been reported in the literature [5, 15, 26, 28-31, 34-36, 38]. Lymph node metastasis (10%) was evaluated in 1 patient with mucoepidermoid carcinoma in our study.…”

Section: Discussionmentioning

confidence: 99%

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Lacrimal Sac Tumors: A Case Series

Kadir¹,

Rashid²,

Sultana³

et al. 2021

Ocul Oncol Pathol

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Objective: The aim of the study was to describe the clinical presentation, management strategies, and outcomes in a case series of primary lacrimal sac tumors. Methods: This retrospective study was conducted in Sheikh Fajilatunnessa Mujib Eye Hospital and Training Institute, Bangladesh, from July 1 to December 31, 2020, and included all patients who were evaluated, treated, and followed up for at least 6 months from January 2013 to October 2020. One patient developed a recurrence of the adenocarcinoma of the lacrimal sac after 1 year of primary treatment. Patients’ demographic data were analyzed and reviewed from published articles on lacrimal sac tumors. We assessed patients clinically, followed by radiological evaluation. We also analyzed the biopsy technique, treatment modality, and recurrence. An oncologist reviewed all patients to prepare a plan for adjuvant treatment. Results: Ten patients with lacrimal sac tumors were included in this study. Swelling in the medial canthal region was the most common presenting feature (100%), followed by epiphora (60%) and pain (30%). Open biopsy was preferred over fine-needle aspiration biopsy. Incisional biopsy or complete excisional biopsy was performed for all suspected malignancies. Malignant tumors were found in 7 (70%) cases, and benign tumors in 3 (30%) cases. Non-Hodgkin’s lymphoma (NHL) (40%) was the most common malignant lacrimal sac tumor. Mucosa-associated lymphoid tissue lymphoma was 75%, and diffuse large B-cell lymphoma was 25% among the cases of NHL. Patients with epithelial malignancy were treated with external beam radiation therapy, while NHL patients were treated with chemotherapy (CHOP regimen). Recurrence was noted in 1 case (10%) of epithelial malignancy after 1 year of treatment. Conclusion: Successful management of lacrimal sac tumors requires a high index of suspicion, as these are fatal tumors, often misdiagnosed as dacryocystitis. Nonepithelial malignancies are more predominant than epithelial malignancies, and hematolymphoid tumors are most frequent.

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Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 99%

Lacrimal Sac Tumors: A Case Series

Kadir¹,

Rashid²,

Sultana³

et al. 2021

Ocul Oncol Pathol

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“…Tear films constantly are being produced and circulated over the ocular surface. In detail, tears secreted by the lacrimal gland are distributed to the ocular surface through blinking, and the tear film is drained eventually through the lacrimal duct, which is a small channel that connects the eyes to the nasal cavity. , From there, the tear film is eliminated from the ocular surface through the nose or swallowed into the digestive system. Tear clearance also occurs through evaporation.…”

Section: Anatomy and Physiology Of The Eyementioning

confidence: 99%

Smart Contact Lenses as Wearable Ophthalmic Devices for Disease Monitoring and Health Management

Seo,

Chung,

Kwon

et al. 2023

Chem. Rev.

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The eye contains a complex network of physiological information and biomarkers for monitoring disease and managing health, and ocular devices can be used to effectively perform point-of-care diagnosis and disease management. This comprehensive review describes the target biomarkers and various diseases, including ophthalmic diseases, metabolic diseases, and neurological diseases, based on the physiological and anatomical background of the eye. This review also includes the recent technologies utilized in eyewearable medical devices and the latest trends in wearable ophthalmic devices, specifically smart contact lenses for the purpose of disease management. After introducing other ocular devices such as the retinal prosthesis, we further discuss the current challenges and potential possibilities of smart contact lenses.

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“…It has higher incidence among people of lower socioeconomic status [8]. The causes of acquired obstruction are infection, inflammation, neoplasms and trauma [9].…”

Section: Introductionmentioning

confidence: 99%