Skeletal changes in multiparous mice fed a nutrient-sufficient diet containing cadmium

Acute cadmium administration to rats exerts both immunosuppressive and proinflammatory effects in spleen

“…Namely, the dose of 5 ppm is representative of levels found in cigarette smoke or in some contaminated food (Pillet et al, 2005). This cadmium concentration is also considered as equivalent to the dose of exposure of women in Japan suffering from Itai-Itai disease (Bhattacharyya et al, 1988). The 50 ppm of cadmium is considered as equivalent to the dose of cadmium noted in subjects living in highly polluted areas or that are professionally exposed to this metal (Wang et al, 2003).…”

Cadmium distribution and toxicity in tissues of small rodents

“…On the other hand, in fast-growing rats, a low iron level (6 mg/kg) in their diet caused a significant increase in cadmium accumulation in the liver and kidney (Schü -mann et al, 1996). Calcium Bhattacharyya et al (1988) observed that during the stresses of pregnancy and lactation in adult mice exposed to cadmium (25 and 50 g g -1 ), the calcium content and Ca/dry weight ratio in the femur decreased more than in non-pregnant females exposed to the same doses of cadmium. Friberg et al (1974) discussed the experiment on different groups of rats kept on low and high calcium diets, which were given cadmium chloride in drinking water for 1 or 2 months.…”

“…The mechanism of Cd-induced bone effects is probably different for exposures to low and high doses (Fig. 8) (Bhattacharyya et al, 1988;Kido et al, 1989Kido et al, , 1990). The normal calcification or remodeling of bones may be markedly impaired by high doses of cadmium, and cadmium (i.p.…”

Screening of lactic acid bacteria with potential protective effects against cadmium toxicity

“…Cd exposure causes various toxic effects including skeletal and cardiovascular dysfunctions (Bhattacharyya et al, 1988;TellezPlaza, Navas-Acien, Crainiceanu, & Guallar, 2008), hepatic and renal damage (Hong, Jin, & Zhang, 2004;Koyu, Gokcimen, Ozguner, Bayram, & Kocak, 2006) and reproductive disorders (Rehm & Waalkes, 1988). Previous studies have found that oxidative stress is an important mechanism of Cd toxicity.…”