Skeletal age estimation in a contemporary Western Australian population using the Tanner–Whitehouse method

Maggio, Ariane; Flavel, Ambika; Hart, Robin; Franklin, Daniel

doi:10.1016/j.forsciint.2016.03.042

Cited by 20 publications

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“…Three different methods utilising a variety of bone combinations (RUS or radius, ulna and short bones or metacarpals; carpals only; and combined RUS and carpal methods) are used to assign an overall maturity score that ranges from 0 to 1000, which is then compared to sex specific centile curves to provide an estimate of skeletal maturity (or age) for each individual method Tanner et al 1983). The use of TW3 RUS and TW2 carpal methods have produced the most accurate estimates of age in female and male individuals respectively in a Western Australian population (SEE ±0.09-3.46 years for females, and SEE ±0.02-3.42 years for males) (Maggio et al 2016).…”

Section: Skeletal Age Estimates In Living Juvenilesmentioning

confidence: 99%

Validation of the İşcan method in clinical MSCT scans specific to an Australian population

2019

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Contemporary research in the field of forensic anthropology has been diversified and aided by the use of medical imaging technology, which is increasingly being utilised to produce estimates of chronological age as part of the biological profile of an unidentified deceased individual, or a living individual whose age is contested. Age vii Dedication I would like to dedicate this thesis to my parents, Iwona and Edward Kopczyk. I can say with complete certainty that I would not be where I am today without your bravery, self-sacrifice and dedication to improving my quality of life. I hope that this thesis comes to represent all that you have wished to provide for me. viii TABLE OF CONTENTS List of Figures .

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Section: Skeletal Age Estimates In Living Juvenilesmentioning

confidence: 99%

Validation of the İşcan method in clinical MSCT scans specific to an Australian population

2019

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“…The limitations of this study include the following:The fact that we did not review hospital notes to ascertain full health in the children (although radiology and ED notes were scrutinised);The exclusion of certain age groups, namely those under 2 years old in females, those under 2.5 years in males and individuals of both sexes aged 15 years or older. In order to save time and eliminate subjectivity, this pragmatic study was performed using BoneXpert; however, this software tool is unable to read images from younger age groups due to limited ossification or non-ossification of epiphyses, while its dependability is questionable when used on older age groups [43];Height and weight and pubertal stage of recruited children were not recorded; it is said that that body mass index affects the rate of skeletal maturation [19, 20]; the prevalence of overweight and obese children is well documented to be rising [44] and should be considered in prospective studies of bone age assessment;We do not know the precise socioeconomic status of the reference children, although those recruited for G&P were said to have “good” socioeconomic status;We used self-reported ethnicity; non-Caucasians were a minority in the current study, yet some researchers have shown that ethnicity is more accurately self-reported in groups other than Caucasian [45–47]; and finally,This study did not set out to be and should not be regarded as a validation study of BoneXpert, since the mean absolute and root mean squared errors were not calculated. Rather, we aimed to correlate G&P and TW3 against known CA of a healthy modern population and found that G&P remains reliable (consistent with the results of a recent systematic review) [48].…”

Section: Discussionmentioning

confidence: 99%

“…Height and weight and pubertal stage of recruited children were not recorded; it is said that that body mass index affects the rate of skeletal maturation [19, 20]; the prevalence of overweight and obese children is well documented to be rising [44] and should be considered in prospective studies of bone age assessment;…”

Section: Discussionmentioning

confidence: 99%

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Applicability of two commonly used bone age assessment methods to twenty-first century UK children

Alshamrani

Offiah

2019

Eur Radiol

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ObjectivesTo assess the effect of secular change on skeletal maturation and thus on the applicability of the Greulich and Pyle (G&P) and Tanner and Whitehouse (TW3) methods.MethodsBoneXpert was used to assess bone age from 392 hand trauma radiographs (206 males, 257 left). The paired sample t test was performed to assess the difference between mean bone age (BA) and mean chronological age (CA). ANOVA was used to assess the differences between groups based on socioeconomic status (taken from the Index of Multiple Deprivation).ResultsCA ranged from 2 to 15 years for females and 2.5 to 15 years for males. Numbers of children living in low, average and high socioeconomic areas were 216 (55%), 74 (19%) and 102 (26%) respectively. We found no statistically significant difference between BA and CA when using G&P. However, using TW3, CA was underestimated in females beyond the age of 3 years, with significant differences between BA and CA (− 0.43 years, SD 1.05, p = < 0.001) but not in males (0.01 years, SD 0.97, p = 0.76). Of the difference in females, 17.8% was accounted for by socioeconomic status.ConclusionNo significant difference exists between BoneXpert-derived BA and CA when using the G&P atlas in our study population. There was a statistically significant underestimation of BoneXpert-derived BA compared with CA in females when using TW3, particularly in those from low and average socioeconomic backgrounds. Secular change has not led to significant advancement in skeletal maturation within our study population.Key Points • The Greulich and Pyle method can be applied to the present-day United Kingdom (UK) population. • The Tanner and Whitehouse (TW3) method consistently underestimates the age of twenty-first century UK females by an average of 5 months. • Secular change has not advanced skeletal maturity of present-day UK children compared with those of the mid-twentieth century. Electronic supplementary materialThe online version of this article (10.1007/s00330-019-06300-x) contains supplementary material, which is available to authorized users.

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“…Auch in der heutigen Zeit kann der GP-Atlas mit seinen Referenzbildern zur Knochenalterbestimmung verwendet werden [7]. Tanner und Whitehouse (TW) veröffentlichten 1962 ebenfalls eine Methode zur Bestimmung des Skelettalters anhand konventioneller Röntgenaufnahmen, deren überarbeitete Versionen (TW2 und TW3) noch heute genutzt werden [8]. Bei der TW-Methode werden verschiedene Knochen der Hand und des Handgelenks ihrer Reifung nach in Stadien eingeteilt.…”

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Applicability of Magnetic Resonance Imaging for Bone Age Estimation in the Context of Medical Issues

Diete

Wabitsch²,

Denzer³

et al. 2020

Rofo

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Objective The determination of bone age is a method for analyzing biological age and structural maturity. Bone age estimation is predominantly used in the context of medical issues, for example in endocrine diseases or growth disturbance. As a rule, conventional X-ray images of the left wrist and hand are used for this purpose. The aim of the present study is to investigate the extent to which MRI can be used as a radiation-free alternative for bone age assessment. Methods In 50 patients, 19 females and 31 males, in addition to conventional left wrist and hand radiographs, MRI was performed with T1-VIBE (n = 50) and T1-TSE (n = 34). The average age was 11.87 years (5.08 to 17.50 years). Bone age assessment was performed by two experienced investigators blinded for chronological age according to the most widely used standard of Greulich and Pyle. This method relies on a subjective comparison of hand radiographs with gender-specific reference images from Caucasian children and adolescents. In addition to interobserver and intraobserver variability, the correlation between conventional radiographs and MRI was determined using the Pearson correlation coefficient. Results Between the bone age determined from the MRI data and the results of the conventional X-ray images, a very good correlation was found for both T1-VIBE with r = 0.986 and T1-TSE with r = 0.982. Gender differences did not arise. The match for the interobserver variability was very good: r = 0.985 (CR), 0.966 (T1-VIBE) and 0.971 (T1-TSE) as well as the match for the intraobserver variability for investigator A (CR = 0.994, T1-VIBE = 0.995, T1-TSE = 0.998) and for investigator B (CR = 0.994, T1-VIBE = 0.993, T1-TSE = 0.994). Conclusion The present study shows that MRI of the left wrist and hand can be used as a possible radiation-free alternative to conventional X-ray imaging for bone age estimation in the context of medical issues. Key points: Citation Format

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Skeletal age estimation in a contemporary Western Australian population using the Tanner–Whitehouse method

Cited by 20 publications

References 22 publications

Validation of the İşcan method in clinical MSCT scans specific to an Australian population

Validation of the İşcan method in clinical MSCT scans specific to an Australian population

Applicability of two commonly used bone age assessment methods to twenty-first century UK children

Applicability of Magnetic Resonance Imaging for Bone Age Estimation in the Context of Medical Issues

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