Sistema de aglutinación con látex para el diagnóstico rápido de la leptospirosis en Cuba

Obregón, Ana Margarita; Fernández, Carmen; Rodríguez, Islay; Balbis, Yinia; Martínez, Beatriz Cantelar; Rodríguez, José

doi:10.1590/s1020-49892004001000005

Cited by 6 publications

(2 citation statements)

References 7 publications

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“…Haematological evaluation showed leucopenia, and thrombocytopenia; other test results are shown in Table 1. [12]. Chikungunya infection was confirmed with RT-PCR (90% sensitivity, 100% specificity) [13].…”

Section: Case Presentationmentioning

confidence: 94%

Fatal Dengue, Chikungunya and Leptospirosis Co-Infection: The Febrile Patient in Tropical Areas, Importance of Co-Infection Assessment

Cardona-Ospina¹,

Ce²,

Vásquez-Serna³

et al. 2018

Preprint

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Background: The febrile patient from tropical areas, in which emerging arboviruses are endemic, represent a diagnostic challenge and potential co-infections with other pathogens (i.e bacteria or parasites) are usually overlooked. Objectives: We present a case of an elderly woman diagnosed with dengue, chikungunya and Leptospira interrogans co-infection. Study Design: Case report. Results: An 87-year old woman from Colombia complained of upper abdominal pain, arthralgia, myalgia, hyporexia, malaise and intermittent fever accompanied with progressive jaundice. She had a medical history of chronic heart failure (Stage C, NYHA III), without documented cardiac murmurs, right bundle branch block, non-valvular atrial fibrillation, hypertension, and chronic venous disease. Her cardiac and pulmonary status quickly deteriorated after 24 hours of her admission without electrocardiographic changes and she required ventilatory and vasopressor support. In the next hours the patient evolved to pulseless electrical activity and then she died. Dengue IgM, NS1 ELISA, MAT for Leptospira interrogans and RT-PCR for chikungunya, were positive. Discussion: This case illustrates a multiple co-infection in a febrile patient from a tropical area of Latin America that evolved to death.

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Section: Case Presentationmentioning

confidence: 94%

Fatal Dengue, Chikungunya and Leptospirosis Co-Infection: The Febrile Patient in Tropical Areas, Importance of Co-Infection Assessment

Cardona-Ospina¹,

Ce²,

Vásquez-Serna³

et al. 2018

Preprint

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show abstract

“…Dengue IgM-antibodies (44.4% sensitivity, 99.1 specificity) and non-structural protein 1 (NS1) dengue protein through enzyme-linked immunosorbent assay (ELISA) (93.9% sensitivity, 97.4% specificity) were both positive [11]. Additionally, titers against Leptospira interrogans (serogroup Tarassovi, serovar Tarassovi, 1:400) were detected through non-paired microagglutination test (MAT) (93.8% sensitivity, 90.4% specificity) [12]. Chikungunya infection was confirmed with reverse transcription polymerase chain reaction (RT-PCR) (90% sensitivity, 100% specificity) [13].…”

Section: Case Presentationmentioning

confidence: 99%

Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas

et al. 2018

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The febrile patient from tropical areas, in which emerging arboviruses are endemic, represents a diagnostic challenge, and potential co-infections with other pathogens (i.e., bacteria or parasites) are usually overlooked. We present a case of an elderly woman diagnosed with dengue, chikungunya and Leptospira interrogans co-infection. Study Design: Case report. An 87-year old woman from Colombia complained of upper abdominal pain, arthralgia, myalgia, hyporexia, malaise and intermittent fever accompanied with progressive jaundice. She had a medical history of chronic heart failure (Stage C, New York Heart Association, NYHA III), without documented cardiac murmurs, right bundle branch block, non-valvular atrial fibrillation, hypertension, and chronic venous disease. Her cardiac and pulmonary status quickly deteriorated after 24 h of her admission without electrocardiographic changes and she required ventilatory and vasopressor support. In the next hours the patient evolved to pulseless electrical activity and then she died. Dengue immunoglobulin M (IgM), non-structural protein 1 (NS1) enzyme-linked immunosorbent assay (ELISA), microagglutination test (MAT) for Leptospira interrogans and reverse transcription polymerase chain reaction (RT-PCR) for chikungunya, were positive. This case illustrates a multiple co-infection in a febrile patient from a tropical area of Latin America that evolved to death.

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A comparison between polymerase chain reaction (PCR) and traditional techniques for the diagnosis of leptospirosis in bovines

Hernández-Rodríguez

Díaz

Dalmau

et al. 2011

Journal of Microbiological Methods

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Sistema de aglutinación con látex para el diagnóstico rápido de la leptospirosis en Cuba

Cited by 6 publications

References 7 publications

Fatal Dengue, Chikungunya and Leptospirosis Co-Infection: The Febrile Patient in Tropical Areas, Importance of Co-Infection Assessment

Fatal Dengue, Chikungunya and Leptospirosis Co-Infection: The Febrile Patient in Tropical Areas, Importance of Co-Infection Assessment

Fatal Dengue, Chikungunya and Leptospirosis: The Importance of Assessing Co-infections in Febrile Patients in Tropical Areas

A comparison between polymerase chain reaction (PCR) and traditional techniques for the diagnosis of leptospirosis in bovines

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