Tuberculosis or TB is an infectious disease in public health. The case-finding rate in Riau was only 39% and Pekanbaru only 37.5%. This objective is to analyze the political commitment of regional leaders in the effort to control TB. This research was qualitative, subjects were 1 manager in the Health office, 1 staff, 2 managers of Public Health Centre. Data collection was carried out by interview and document study. The results show there is political commitment related to the TB program, recording and reporting standards with the SITB, a program plan is drawn up every year, such as human resources, budget, facilities and infrastructure, and involving the community. The conclusion is the political commitment of the leadership in TB is quite good but it is suggested to increase in the allocation of funding, human resources must consider.