Sirolimus-eluting stents in the treatment of chronic total coronary occlusions

Abstract

Implantation of the Cypher stent reduces the restenosis rate and seems to be a safe and effective tool for the treatment of chronic total coronary occlusions.

Hotline update of clinical trials and registries presented at the German Cardiac Society meeting 2008

“…Therefore, the authors concluded that there is no evidence that immediate (\30 days) ICD implantation after myocardial infarction improves mortality. (Presenter: D. Andresen, Berlin) GERSHWIN Percutaneous coronary intervention using sirolimuseluting stents (SES) has been shown to reduce instent-restenosis compared to bare metal stents (BMS) [2]. The objective of the GERSHWIN (German stent health outcome and economics within normal practice) study was to study clinical benefit (MACE: death, myocardial infarction, bypass therapy, re-PCI in the target vessel), costs, and quality of life using SES or BMS [3] Death from ischemic heart diseases (ICD-10 I20-I25), consisting largely of acute myocardial infarction (I20) and chronic ischemic heart disease (I25) showed strong regional variation with high figures ([155 cases per 100,000 men) in the north-east and the Saarland, and \100 cases in the south, particularly in the south-west of Germany.…”

Hotline update of clinical trials and registries presented at the German Cardiac Society Meeting 2009

“…Percutaneous coronary intervention using sirolimus-eluting stents (SES) has been shown to reduce in-stent-restenosis compared to bare metal stents (BMS) [2]. The objective of the GERSHWIN (German stent health outcome and economics within normal practice) study was to study clinical benefit (MACE: death, myocardial infarction, bypass therapy, re-PCI in the target vessel), costs, and quality of life using SES or BMS [3].…”