Single-Session Prolonged Alcohol-Retention Sclerotherapy for Large Hepatic Cysts

Abstract

Long retention of the alcohol in a single-injection technique is safe and effective. Two-hour alcohol retention has a comparable efficacy to that of 4-hour retention.

Sclerotherapy of simple hepatic cysts by repeated aspiration and alcohol instillation

“…Previous reports have documented many complications associated with alcohol sclerotherapy, such as dizziness, nausea, headache, vomiting, flushing, deep sleep, and drops in blood pressure (14). In the present series, some symptoms and signs of drunkenness were also noted following the repeated rapid aspiration/instillation sclerotherapy.…”

“…In recent years, researchers have com- (14). These data clearly indicate that the RAAIS procedure has better efficacy than alcohol-retention sclerotherapy in the management of large SHCs.…”

“…In addition, because of incomplete aspiration of cyst fluid, the residual cyst fluid markedly dilutes the alcohol concentration, thus affecting its therapeutic efficacy (11). Therefore, there are increasing efforts to improve the outcome of alcohol sclerotherapy, including modulating ethanol concentration and volume, duration of ethanol exposure, and number of sclerotherapy sessions (12)(13)(14)(15)(16). For instance, insufficient alcohol concentration, volume, or short contact time with the cyst epithelia tends to result in a high recurrence rate (17), whereas an increased amount of alcohol or a longer exposure period may pose a higher risk of host toxicity (14).…”

“…Therefore, there are increasing efforts to improve the outcome of alcohol sclerotherapy, including modulating ethanol concentration and volume, duration of ethanol exposure, and number of sclerotherapy sessions (12)(13)(14)(15)(16). For instance, insufficient alcohol concentration, volume, or short contact time with the cyst epithelia tends to result in a high recurrence rate (17), whereas an increased amount of alcohol or a longer exposure period may pose a higher risk of host toxicity (14). We hypothesized that rapid elevation of alcohol to a sufficiently high concentration in a short period may result in a safer and more efficient sclerotherapy procedure with better outcomes.…”

Effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts

“…Image-guided alcohol sclerotherapy has been used to treat simple renal cysts and liver cysts, as well as cystic thyroid and parathyroid nodules with considerably high success rates for a very long time and is considered as a safe and effective method with few side effects (11)(12)(13)(14)(15). This study is similar in many ways to the treatment efforts for renal and liver cysts involving treatment of simple cysts by single-session sclerotherapy using alcohol and reaspiration of the cavity.…”