Single oral dose fluconazole compared with conventional clotrimazole topical therapy of Candida vaginitis

In Vitro and in Vivo Antifungal Activities of the Eight Steroid Saponins from Tribulus terrestris L. with Potent Activity against Fluconazole-Resistant Fungal

“…Candidal vaginitis is predominantly caused by strains of C. albicans (90%), [5][6][7] and remains to be a common problem in immunocompetent or healthy women. So we also observed the in vivo activity of TTS-12 against fluconazole-resistant C. albicans.…”

Comparison of efficacy, safety and cost-effectiveness of clotrimazole 1% cream and sertaconazole 2% cream in patients suffering from of mild to moderate tinea corporis, attending tertiary care hospital out-patient department: a randomized, open-labeled, comparative, parallel group trial

“…5,6 Sertaconazole nitrate is the new topical azole antifungal, found to be more effective than conventional azoles. This recently developed antifungal is characterized by broad spectrum of action against yeasts, dermatophytes and Gram-positive bacteria as well.…”

Fluconazole Susceptibility of Vaginal Isolates Obtained from Women with Complicated Candida Vaginitis: Clinical Implications

“…In vitro fluconazole resistance developed in 2 of 18 initially susceptible C. glabrata isolates following fluconazole exposure. Susceptibility testing for women with complicated Candida vaginitis appears to be unjustified.Candida vaginitis remains a common problem in immunocompetent, healthy women and is predominantly caused by strains of Candida albicans (Ͼ90%) (14,17,19). Only a minority of cases (Ͻ10%) are caused by non-C. albicans Candida species, usually C. glabrata, and despite considerable debate, there is little evidence of a significant increase in infection rates due to the non-C. albicans Candida species (14,17,19).…”

“…Only a minority of cases (Ͻ10%) are caused by non-C. albicans Candida species, usually C. glabrata, and despite considerable debate, there is little evidence of a significant increase in infection rates due to the non-C. albicans Candida species (14,17,19). Given the reports of refractory oral and esophageal candidiasis caused by fluconazole-resistant C. albicans strains and, less commonly, non-C. albicans Candida species, it is important to monitor the fluconazole susceptibilities of vaginal isolates of the various Candida species (1,3,5,8,11).…”