Three different Photonic Crystal Fiber (PCF) gas sensors are designed to detect five different gases for a wide range of wavelengths. The three unique configurations are designed based on four outer Elliptical cores PCF (4E-PCF), four outer Circular cores (4C-PCF) PCF, and different Eight Elliptical cores PCF (8E-PCF) to analyze and sense the light interface with applied gases. For three proposed gas sensors, the sensing parameters for five different hazardous gases, such as relative sensitivity, effective area, birefringence and dispersion, are acquired. The five different gases considered for the sensor investigation are Sulfur trioxide [SO3] (20oC), Tetracholorosilane [SiCl4], Tetracholoromethane [CCl4], Turpentine [C10H16], Tin Terra chloride [SnCl4]. Among the three designs, 8E-PCF yields a maximum sensitivity of 75.75%, an effective area of 2.45µm2, and a birefringence of 0.0421 for SnCl4 gas.