Single-dose amoxicillin therapy of uncomplicated pediatric urinary tract infections

Avner, Ellis D.; Ingelfinger, Julie R.; Herrin, John T.; Link, David A.; Marcus, Eugenia; Tolkoff-Rubin, Nina; Russell-Getz, Linda; Rubin, Robert H.

doi:10.1016/s0022-3476(83)80207-8

Cited by 30 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, we were unable to find any evidence that suggests a longer course of antibiotic therapy (11–14 days) is more effective than a shorter course of therapy (7–10 days) in the treatment of pediatric UTIs. Multiple studies demonstrate that a short course of antibiotic therapy has low rates of reinfection and treatment failure [39–41]. Thus, in many situations, widespread adoption of a shorter treatment course would deliver effective and less costly care.…”

Section: Discussionmentioning

confidence: 99%

Pediatric urinary tract infections: an analysis of hospitalizations, charges, and costs in the USA

et al. 2010

View full text Add to dashboard Cite

This study evaluates the impact of pediatric uninary tract infection (UTI)s on the economy and inpatient healthcare utilization in the USA. A retrospective analysis of patient demographics and hospital economics was performed on children less than 18 years of age admitted with a UTI between 2000 and 2006 using the Healthcare Cost and Utilization Project Kids’ Inpatient Database. Our results were stratified as follows. Hospital admissions—nearly 50,000 children/year were admitted with a UTI. Pediatric UTIs represented 1.8% of all pediatric hospitalizations. Seventy-three percent of patients were female and 40% were under 1 year of age. Payer information—from 2000 to 2006, pediatric insurance coverage shifted from the private sector to the public sector. Hospital cost—in 2000, estimated hospital costs for UTIs were $2,858 per hospitalization and rose to $3,838 by 2006. Mean hospital charges increased from $6,279 to $10,489 per stay. By 2006, aggregate hospital charges exceeded $520 million. Our results indicate that UTIs are among the most common pediatric admission diagnoses. Hospitalization is more common in females and younger children. Since 2000, hospital charges for UTIs increased disproportionately to hospital costs. Over time, more children hospitalized with a UTI depend on public agencies to cover healthcare expense. More efforts are needed to evaluate cost-effective strategies for evaluation and treatment of UTIs.

show abstract

Section: Discussionmentioning

confidence: 99%

Pediatric urinary tract infections: an analysis of hospitalizations, charges, and costs in the USA

et al. 2010

View full text Add to dashboard Cite

show abstract

“…We compared <3 days of treatment to 7-14 days of treatment, whereas Michael et al compared 2-4 days of treatment to 7-14 days of treatment and excluded 11 studies comparing single-dose or single-day treatment to standard duration treatment. [7][8][9][10][11][12][13][14][15][16][17] The reasons for this exclusion are unclear, although we presume that they felt single-dose or single-day treatment was not a fair comparison with 7-14 day treatment. However, a number of randomised controlled trials (RCTs) made this comparison, suggesting that clinicians are, in fact, interested in the potential efficacy (and significantly increased ease and savings) of single-dose or single-day treatment.…”

Section: Glucose Metabolism In Sleep Disordered Breathingmentioning

confidence: 99%