OBJECTIVE: Urinary tract infection (UTI) is the most common serious bacterial infection in infants. To use resources optimally, factors contributing to costs through length of stay (LOS) must be identifi ed. This study sought to identify clinical and health system factors associated with long LOS in infants with UTI.
METHODS:Using a case-control design, we included infants <6 months old hospitalized with UTI. Cases had LOS ≥96 hours; controls had LOS <96 hours. Clinical and health system variables were extracted from medical records. Cases and controls were compared by using comparative statistics and multiple logistic regression analysis.
RESULTS:Cases (n = 71) and controls (n = 71) did not differ by gender; cases were more likely to be younger (4.2 vs 7.1 weeks, P = .04), born preterm (13% vs 3%, P = .03), have known genitourinary disease (17% vs 4%, P = .01), an ultrasound (85% vs 68%, P = .02) or voiding cystourethrogram (VCUG) (61% vs 34%, P = .001) ordered, longer wait for VCUG (53 vs 27 hours, P = .002), consult requested (54% vs 10%, P < .001), and longer duration of intravenous (IV) antibiotics (125 vs 62 hours, P < .001). Multiple logistic regression demonstrated that cases were more likely to be premature (odds ratio [OR] 7.6), have known genitourinary disease (OR 7.3), and have VCUG ordered in the hospital (OR 4.5).
CONCLUSIONS:Infants who are older, are born full term, have no genitourinary disease, receive shorter courses of IV antibiotics, and do not have a VCUG ordered have shorter stays and may be eligible for a short-stay unit. Earlier transition to oral antibiotics and delayed ordering of a VCUG may decrease LOS.
Predictors of Long Length of Stay in Infants Hospitalized With Urinary Tract Infection
(Continued on last page)Urinary tract infection (UTI) is the most common serious bacterial infection in young infants.1 Approximately 7% of girls and 2% of boys will have a UTI by 6 years of age.2 Although most UTIs can be managed effectively on an outpatient basis, infants are often hospitalized for treatment.3 UTI accounts for ∼8% of infant infectious disease hospitalizations and ∼2% of all pediatric hospitalizations.4,5 Although rates and duration of hospitalization for UTI have remained fairly constant over the past decade, hospital costs have risen by ∼34% and continue to impose a signifi cant fi nancial burden on the health care system.
5To use health care resources optimally and reduce costs wherever possible, it is important to identify factors contributing to costs through hospitalization. Previous studies using a large administrative database have investigated selected factors contributing to length of stay (LOS) for UTI and found that children who were younger, were hospitalized at an institution without clinical practice guidelines, www.hospitalpediatrics.org or received initial empiric antibiotic therapy to which the uropathogen was not susceptible had greater LOS.6,7 We sought to identify additional clinical and health system factors associated with long LOS in infants hospita...