Síndrome hepatopulmonar en pacientes con hepatopatía avanzada: estudio de 24 casos

The utility of the macro-aggregated albumin lung perfusion scan in the diagnosis and prognosis of hepatopulmonary syndrome in cirrhotic patients candidates for liver transplantation

“…Arguedas et al observed a strong negative correlation with PaO 2 while breathing room air, a positive correlation with A-a PO 2 and, similar to our study, a weak correlation with PaO 2 while breathing 100% O 2 (8). Finally, Swanson et al found the same correlations with PaO 2 while breathing room air, A-a PO 2 and PaO 2 while breathing 100% O 2 (9). The 99m Tc-MAA was not correlated with the calculated degree of oxygen shunt in any of the studies (Table III).…”

“…In this context, there are some studies linking the increased brain uptake of 99m Tc-MAA to increased mortality among HPS patients (6)(7)(8). In an attempt to validate its ability to quantify IPVD, its correlations with different respiratory parameters that could measure HPS severity, such as the PaO 2 while breathing 100% oxygen, A-a O 2 , estimated degree of oxygen shunt and corrected diffusing capacity for carbon monoxide (DLCOco), have been analyzed; however, the information is scarce and inconclusive (5)(6)(7)(8)(9).…”