Síndrome hemofagocítico. Estudio de 16 casos

Barbón, S. Rubio; García, María Esther González; Basanta, Maria; Huerta, A. J. González

doi:10.1016/j.medcli.2008.09.026

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…To our knowledge, no case of VL-HIV coinfection with psychiatric disorder at presentation were published in the medical literature. On the other hand, HLH can, unusually, present with psychiatric changes (22,23). Regarding the clinical and biological presentation of our patient, we discussed the diagnosis of an HIV-associated immune reconstitution inflammatory syndrome (IRIS).…”

Section: Discussionmentioning

confidence: 92%

Case Report: Leishmania and HIV Co-Diagnosis: How to Understand Medical History?

et al. 2021

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We report a case of a severe visceral leishmaniasis revealing an HIV-1 infection presenting as an acute primary infection. A young French man living in Paris with history of unprotected sex with a recent male partner and recent travel in Greece was admitted in our Infectious Diseases Department, presenting with acute febrile psychotic disorder, and positive HIV-1 serology with high viral load, very low CD4+ T-cells count and a western blot pattern suggesting an acute infection. The psychotic disorder was finally related to hemophagocytic lymphohistiocytosis diagnosed on bone marrow aspiration, supposedly secondary to HIV acute primary infection. The progressive worsening of pancytopenia despite antiretroviral treatment and the persistence of fever, chills and sweat led to the diagnosis of visceral leishmaniasis through bone marrow biopsy and leishmanial serology. He was treated with intravenous liposomal amphotericin B with quick improvement. We discuss the way HIV infection and visceral leishmaniasis may have interact to lead to the clinical presentation of our patient.

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Section: Discussionmentioning

confidence: 92%

Case Report: Leishmania and HIV Co-Diagnosis: How to Understand Medical History?

et al. 2021

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Adult haemophagocytic syndrome

et al. 2014

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Hemophagocytic Lymphohistiocytosis After Greenlight Laser Prostate Surgery

Chander¹,

Chaudhary²,

Kumari³

et al. 2022

Cureus

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Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening systemic inflammatory disease. Multiple risk factors have been defined for the manifestation of HLH. While infection remains the top risk factor, having multiple surgical procedures has also been suggested as a potential risk factor for HLH. Our patient presented with generalized weakness, weight loss, and fatigue after having a greenlight laser prostatectomy for benign prostate hypertrophy; the patient deteriorated rapidly and was found to fulfill the HLH 2004 and modified criteria. We believe this patient had a rare bone marrow disorder with a rare complicated clinical and laboratory presentation.

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Síndrome hemofagocítico. Estudio de 16 casos

Cited by 3 publications

References 7 publications

Case Report: Leishmania and HIV Co-Diagnosis: How to Understand Medical History?

Case Report: Leishmania and HIV Co-Diagnosis: How to Understand Medical History?

Adult haemophagocytic syndrome

Hemophagocytic Lymphohistiocytosis After Greenlight Laser Prostate Surgery

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