Síndrome celiaco

Meneghello, Julio; Undurraga, O

doi:10.4067/s0370-41061946000500004

Cited by 1 publication

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“…Actualmente, la prevalencia de la enfermedad en Europa y Estados Unidos de Norteamérica se estima que es de 1%, sin embargo, en América del Sur en general y en Chile, existe escasa información sobre la prevalencia poblacional de esta enfermedad, y no se dispone de reportes de prevalencia de la enfermedad en población indígena. El primer reporte que pudimos identificar en Chile es de 1947, donde se describe en un niño un cuadro con presencia de síntomas gastrointestinales que comenzaron luego de 2 años de vida y a los 5 años ya tenía claros signos de desnutrición y patologías secundarias a la mala absorción como osteoporosis; el diagnóstico se hizo en base a clínica y exámenes radiológicos 17 .…”

Section: Aspectos Históricos A) Enfermedad Celíacaunclassified

El gluten: Su historia y efectos en la enfermedad celíaca

Parada

Araya

2010

Rev. méd. Chile

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History of gluten and its effects on celiac disease The global prevalence of celiac disease is of one person per 250 inhabitants. The disease is induced by gluten, a peptide contained in wheat, rye and barley that during small intestinal digestion generates smaller peptides. Some of these are resistant to hydrolysis and cross through the epithelium into the mucosa, inducing a cascade of immune reactions leading to the appearance of the disease in susceptible individuals. Gluten appeared as a consequence of agricultural practices initiated 10000 years ago in the Fertile Crescent of southwest Asia. Celiac disease epidemiology is complicated since consumption of gluten differs depending on the origin of populations. Treatment of celiac disease consists of withdrawing gluten from the diet, a task that becomes difficult in the long term. The concept of gluten-free food has changed along time. This article updates the concept of celiac disease, the history of gluten consumption in the world, the characteristics of a gluten free diet and the difficulties to adhere to it.

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Section: Aspectos Históricos A) Enfermedad Celíacaunclassified