Simultaneous separation of artesunate and mefloquine in fixed-dose combination tablets by CZE-UV

Souza, Jéssica de; Chellini, Paula Rocha; Viçosa, Alessandra Lifsitch; Souza, Marcus V. N. de; Oliveira, Marcone Augusto Leal de

doi:10.1039/d0ay01755h

Cited by 4 publications

(1 citation statement)

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“…Then, according to the characteristics of different separation modes, some important basic operating conditions are optimized to explore their impacts on some indicators such as separation degree, resolution, repeatability, and separation time, and finally, obtain the best separation conditions [43]. Typical examples are listed in Table 2 [44][45][46][47][48][49][50][51][52][53][54][55][56][57] and systematically discussed under the diverse separation modes in the following sections.…”

Section: Capillary Electrophoresis (Ce)mentioning

confidence: 99%

Design of experiment techniques for the optimization of chromatographic analysis conditions: A review

et al. 2022

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Design of experiment (DoE) techniques have been widely used in the field of chromatographic parameters optimization as a valuable tool. A systematic literature review of the available DoE techniques applied to the development of a chromatographic analysis method is presented in this paper. First, the most common available designs and the implementation steps of DoE are comprehensively introduced. Then the studies in recent 10 years for the application of DoE techniques in various chromatographic techniques are discussed, such as capillary electrophoresis, liquid chromatography, gas chromatography, thin‐layer chromatography, and high‐speed countercurrent chromatography. Current problems and future outlooks are finally given to provide a certain inspiration of research in the application of DoE techniques to the different chromatographic techniques field. This review contributes to a better understanding of the DoE techniques for the efficient optimization of chromatographic analysis conditions, especially for the analysis of complex systems, such as multicomponent drugs and natural products.

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Section: Capillary Electrophoresis (Ce)mentioning

confidence: 99%

Design of experiment techniques for the optimization of chromatographic analysis conditions: A review

et al. 2022

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Determination of artemisinin and its analogs in Artemisia annua extracts by capillary electrophoresis – Mass spectrometry

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Pesti

Andrási

et al. 2021

Journal of Pharmaceutical and Biomedical Analysis

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Mixture design of an electrolyte system for the simultaneous separation of Cl⁻, SO₄²⁻, NO₃⁻, NO₂⁻, and HCO₃⁻ in shrimp-farming water by CZE-UV

et al. 2023

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Simultaneous separation of artesunate and mefloquine in fixed-dose combination tablets by CZE-UV

Abstract: A novel method was proposed for simultaneous determination of artesunate (ATS) and mefloquine (MFQ) in fixed-dose combination tablets by capillary zone electrophoresis with simultaneous direct and indirect detection by ultraviolet...

Cited by 4 publications

References 13 publications

Design of experiment techniques for the optimization of chromatographic analysis conditions: A review

Design of experiment techniques for the optimization of chromatographic analysis conditions: A review

Determination of artemisinin and its analogs in Artemisia annua extracts by capillary electrophoresis – Mass spectrometry

Mixture design of an electrolyte system for the simultaneous separation of Cl⁻, SO₄²⁻, NO₃⁻, NO₂⁻, and HCO₃⁻ in shrimp-farming water by CZE-UV

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Simultaneous separation of artesunate and mefloquine in fixed-dose combination tablets by CZE-UV

Abstract: A novel method was proposed for simultaneous determination of artesunate (ATS) and mefloquine (MFQ) in fixed-dose combination tablets by capillary zone electrophoresis with simultaneous direct and indirect detection by ultraviolet...

Cited by 4 publications

References 13 publications

Design of experiment techniques for the optimization of chromatographic analysis conditions: A review

Design of experiment techniques for the optimization of chromatographic analysis conditions: A review

Determination of artemisinin and its analogs in Artemisia annua extracts by capillary electrophoresis – Mass spectrometry

Mixture design of an electrolyte system for the simultaneous separation of Cl−, SO42−, NO3−, NO2−, and HCO3− in shrimp-farming water by CZE-UV

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Mixture design of an electrolyte system for the simultaneous separation of Cl⁻, SO₄²⁻, NO₃⁻, NO₂⁻, and HCO₃⁻ in shrimp-farming water by CZE-UV