High-fat diet (HFD) intake leads to increased plasma cholesterol concentrations, as well as atherosclerotic lesions. Therefore, HFD constitutes a serious threat to the cardiovascular health of human beings (Zeljković et al., 2019). Hyperlipidemia is a condition that implicates several serum lipoprotein abnormalities such as increase levels of triglyceride (TG), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and very low-density lipoprotein cholesterol (VLDLC), as well as decrease high-density lipoprotein cholesterol (HDL-C). In addition to being a common endocrine metabolic disease, hyperlipidemia is one of the major risk factors that cause arteriosclerosis, cerebral stroke, coronary heart disease, myocardial infarction, type 2 diabetes, and renal failure (Panahi et al., 2018;Shao et al., 2017;Sun et al., 2017). Fibrates, statins, bile acid sequestrants, nicotinic acid, and cholesterol absorption inhibitors are commonly used to treat hyperlipidemia; however, these treatments are limited by numerous side effects, including diarrhea, nausea, myositis, and abnormal liver