Simultaneous occurrence of pyogenic granuloma at multiple sites associated with bone loss: Report of a rare case

Mohanty, Gatha; Mohanty, Rinkee; Satpathy, Anurag

doi:10.4103/jisp.jisp_367_17

Cited by 7 publications

(3 citation statements)

References 8 publications

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“…Nodular KS usually shows numerous dome-shaped nodular lesions, unlike PG, which often presents with a single lesion [2]. However, it should be kept in mind that KS may present with a single lesion and PG may show multiple nodules [9,10].…”

Section: Discussionmentioning

confidence: 99%

Pyogenic granuloma and nodular Kaposi’s sarcoma: dermoscopic clues for the differential diagnosis

et al. 2019

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Introduction Pyogenic granuloma (PG), also known as lobular capillary hemangioma, is a benign vascular proliferation of the skin and mucous membranes. PG is usually characterized by a solitary pink to red dome-shaped nodule. The exact etiopathogenesis of the disease is not clearly known [1]. Kaposi's sarcoma (KS) is a low-grade vascular tumor associated with human herpesvirus 8 (HHV8) infection [2]. PG and the nodular form of KS may share similar clinical characteristics. The differential diagnosis of these two entities is essential as both of them differ in prognosis and necessitate different management. Histopathological examination still remains the gold standard in this respect [3]. PG-like KS has been previously demonstrated in several studies [3]. However, to the best of our knowledge, no study investigating the dermoscopic differential diagnosis of PG and KS exists in the literature. Here we aimed to demonstrate dermoscopic clues to differential diagnosis. 2. Materials and methods 2.1. Patients The study was conducted in a tertiary center. Patients with a histopathological diagnosis of PG or nodular KS between January 2017 and November 2018 were included. Demographic, clinical, dermoscopic, and histopathological findings of all the patients were retrospectively reviewed. 2.2. Dermoscopic assessment A thorough dermoscopic examination was performed for all the lesions included and the findings were recorded. The dermoscopic findings observed were described using Kittlerian terminology. Dermoscopic examination was performed with a polarized handheld dermoscope with 10× magnification (Dermlite 4, 3GEN Inc., San Juan Capistrano, CA, USA). Capture of dermoscopic images was performed using a high-resolution mobile camera phone attached to the dermoscope (iPhone 7 Plus, Apple Inc., Cupertino, CA, USA). Background/aim: Pyogenic granuloma (PG)-like nodular Kaposi's sarcoma (KS) has been previously demonstrated in several studies. However, to the best of our knowledge, no original study investigating the dermoscopic differential diagnosis of PG and KS exists in the relevant literature. In this study we aimed to identify dermoscopic findings providing useful clues to differential diagnosis between the two entities. Materials and methods: Patients with histopathologically confirmed PG or nodular KS were included in the study. Demographic, clinical, dermoscopic, and histopathological findings of the cases were retrospectively reviewed. Results: The most common finding observed in PG was red structureless areas (80.00%), followed by intersecting thick white lines (56.66%), ulceration (36.66%), and collarette scale (33.33%). The most common findings detected in nodular KS were polychromatic structures (56.66%) and red (46.66%) and white (13.33%) structureless areas, respectively. Conclusion: Intersecting thick white lines seem to be the strongest dermoscopic clue to PG. Striate surface scaling (n = 6) was a novel finding identified for PG. Here we also described a new vascular pattern (widespread vessels composing a netwo...

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Section: Discussionmentioning

confidence: 99%

Pyogenic granuloma and nodular Kaposi’s sarcoma: dermoscopic clues for the differential diagnosis

et al. 2019

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“…Poor dental hygiene is the most frequent cause of this condition, with tartar deposits or other foreign materials seen in the associated gingival fissure in 75% of cases [4] . Although it is uncommon, pyrogenic granuloma can also affect the lips, mucosa, tongue, and other areas [5,6] . Clinically, PG manifests as an exophytic growth that is uniform, lobulated, and has a sessile or pedunculated base5.…”

Section: Introductionmentioning

confidence: 99%

Treatment of recurrent pyogenic granuloma: Case report with 1.5-year follow-up

Verma¹,

Tewari²,

Tanwar³

et al. 2023

Int. J. Appl. Dent. Sci.

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In young adult females, oral pyogenic granuloma predominates in the second decade of life. The gingiva is the most typical site of involvement. In this case study, a 16-year-old female patient was described who had a painless intraoral growth involving the soft tissue of the lower front teeth that bled profusely when being brushed and interfered with her ability to eat. The growth was surgically removed while under local anaesthesia. The patient's case was monitored for 1.5 years to look for any recurrence in this or other regions and to ensure that his oral health had stabilized.

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“…It is a well known outer sphere oxidant [7,8] and a mild oxidant. Its electron transfer reaction with ascorbic acid [9] glutathione [1]0, citric acid [11], DL-methionine [12], L-cysteine [13], NADH [14] and L-cystine [15] have been studied. In order to examine the oxidative degradation of diclofenac sodium, its oxidation reaction with the above oxidant has been studied.…”

Section: Introductionmentioning

confidence: 99%

Kinetics and Mechanism of Oxidation of Diclofenac Sodium by Keggin Type 12-Tungstocobalt(III) in Aqueous Medium

Sanjana¹,

Patnaik²,

Mohanty³

et al. 2017

Asian J. Chem.

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The kinetics of electron transfer reaction of diclofenac sodium with 12-tungstocobaltate (III) complex has been studied spectrophotometrically over the range 2.0 × 10 -3 ≤ [diclofenac sodium] ≤ 6.0 × 10 -3 mol/L, 6.03 ≤ pH ≤ 8.0 and at 293 ≤ T ≤ 308 K in aqueous medium at constant ionic strength I (0.5 mol/L sodium perchlorate). The electron transfer reaction showed pseudo-first order dependence in [diclofenac sodium] and [12-tungstocobaltate(III)] and less than unit order in [OH -]T. The activation parameters calculated for the electron transfer reaction favoured the formation of a precursor complex between the reactants. The product is characterized by FTIR and NMR spectra and is found to be [2-(2,6-dichloro phenylamino)phenyl]methanol.

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Simultaneous occurrence of pyogenic granuloma at multiple sites associated with bone loss: Report of a rare case

Cited by 7 publications

References 8 publications

Pyogenic granuloma and nodular Kaposi’s sarcoma: dermoscopic clues for the differential diagnosis

Pyogenic granuloma and nodular Kaposi’s sarcoma: dermoscopic clues for the differential diagnosis

Treatment of recurrent pyogenic granuloma: Case report with 1.5-year follow-up

Kinetics and Mechanism of Oxidation of Diclofenac Sodium by Keggin Type 12-Tungstocobalt(III) in Aqueous Medium

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