Simultaneous and direct determination of glyphosate and AMPA in water samples from the hydroponic cultivation of eucalyptus seedlings using HPLC-ICP-MS/MS

Determination of Phosphoethanolamine in Urine with HPLC-ICPMS/MS Using 1,2-Hexanediol as a Chromatographic Eluent

“…As little as 9% v/v was sufficient to elute the hydrophobic derivative under standard ICPMS conditions and instrumental setup without employing any of the components of the organic ICPMS mode while achieving fast separation within <4 min ( k = 7) (Figure ). The instrumental limit of detection was 0.5 μg P L –1 , which is similar to previously reported limits of detection for hydrophilic phosphorous-containing analytes with ICPMS/MS detection. − …”

“…A relatively small number of applications have been reported for chromatographic detection with ICPMS/MS involving phosphorouscontaining compounds. These applications mostly involved the determination of organophosphorus herbicides in nonbiological matrices with simple phosphorous metabolomes 5,7,8 or phosphorous-containing biomolecules in pure standard solution. 4 Phosphoethanolamine is an essential building block for key phospholipids, notably phosphatidylethanolamine, which is implicated in a variety of medical conditions.…”

“…Furthermore, phosphorous speciation analysis using a single quadrupole ICPMS in highly complex matrices such as urine is particularly challenging due to the high abundance of organic compounds containing the above-mentioned interfering elements and the associated formation of polyatomic interferences, which could result in the appearance of chromatographic peaks not attributed to phosphorous-containing species and compromise the selectivity of detection. Indeed, the majority of phosphorous speciation studies performed with a single quadrupole ICPMS involved simple environmental matrices. − Although polyatomic interferences at m / z 31 can be mitigated through the use of a collision/reaction cell, , the most effective solution providing the highest selectivity is the employment of a triple quadrupole ICPMS (ICPMS/MS), where a reaction cell with oxygen as the reaction gas is used and the mass transition 31 → 47 is monitored using two quadrupole mass analyzers, achieving >10-fold improvement in the detection limit over single quadrupole ICPMS. − …”

“… 1 − 3 Although polyatomic interferences at m / z 31 can be mitigated through the use of a collision/reaction cell, 3 , 4 the most effective solution providing the highest selectivity is the employment of a triple quadrupole ICPMS (ICPMS/MS), where a reaction cell with oxygen as the reaction gas is used and the mass transition 31 → 47 is monitored using two quadrupole mass analyzers, achieving >10-fold improvement in the detection limit over single quadrupole ICPMS. 4 − 7 …”

Atomic Spectrometry Update: review of advances in elemental speciation

“…In a second paper the same method was employed to investigate the levels of herbicide in botanical and hydroponic samples, with the aim of establishing a method that was appropriate for use at the Brazilian maximum residue limit for glyphosate in drinking water of 65 μg L −1 . 161 This required SPE of the glyphosate and AMPA using an AE resin (3 g) with an active quaternary ammonium functional group, particle size of 600–750 μm and packed into a glass column (20 cm × 1.5 cm id). Spiked and unspiked samples were applied to the resin at a flow rate of 1.0 mL min −1 and the analytes eluted off with HCl (6 mol L −1 ).…”