The geometric parameters of labyrinth channels play an important role in the hydraulic and anti‐clogging performance of drip emitters. In this study, the flow fields, individual representative sands and sand groups in the labyrinth channel of emitters, with dentation angles of 90°, 60°, 45° and 30°, were firstly simulated using a computational fluid dynamics discrete element method (CFD–DEM) of coupling. Particle tracking velocimetry (PTV) was used to trace individual representative sands. The numerical results were verified with clear water hydraulic performance tests and muddy water anti‐clogging performance tests. The results suggest that the discharge coefficient and flow exponent declined when the dentation angle of the labyrinth channel was reduced. A large number of sand groups were observed to enter the vortex areas and move in a circular manner. The time it took for particles to pass through the labyrinth channel lengthened when the velocity decreased and as a result, the probability of emitter clogging increased. Therefore, by using a recommended angle range of 90° to 60° and a combined higher hydraulic performance level, emitters were less likely to clog. It was a novel approach to adopt a CFD–DEM coupling method to conduct numerical analysis of individual sand particles and sand groups in the investigation of emitter anti‐clogging issues. The findings will increase the design efficiency of flow channels and will save human and material resources. © 2018 John Wiley & Sons, Ltd.