This study aimed to investigate the influence of different pressures on the distribution of particle sizes of deposited sediments and discharged sands in the process of flushing, using cylindrical labyrinth channel emitters. Flushing was performed for 2 min before each irrigation under 0.15, 0.20, 0.25 and 0.30 MPa of pressure. The variation in flow discharge with irrigation times was measured after flushing, and a Malvern laser particle size analyser was employed to analyse the gradation of discharged sands. The results of this study suggested that irrigation time with normal outflow rate was remarkably extended and the anti‐clogging performance of emitters was obviously promoted by the increase in flushing pressures. Moreover, the emitters were sensitive to particles larger than 6.607 μm in diameter, which tended to be retained in the flow paths. In contrast, particles smaller than 6.607 μm in diameter flowed out of the labyrinth channel easily. Furthermore, the flushing pressure had a major impact on the larger particles of discharged sediments, whereas it had a minor effect on smaller particles. Increasing flushing pressures appropriately could effectively increase the passing rate of larger particles, thereby extending the lifespan of emitters. Therefore, it is advised to perform high‐pressure flushing for 2–3 min before each irrigation to prevent the clogging of emitters. Copyright © 2017 John Wiley & Sons, Ltd.