Simple clinical data are useful in predicting effect of exercise training after myocardial infarction

Abstract

Five simple clinical variables, including infarct size, can assist in the selection of patients for exercise training after myocardial infarction.

Patients with large myocardial infarction gain a greater improvement in exercise capacity after exercise training than those with small to medium infarction

“…Carter and Amundsen reported that there was a significant association between infarction size and exercise capacity, 3 whereas Heldal et al found no significant correlation. 16 In the present study, although the peak serum CPK level significantly correlated with exercise capacity in the univariate analysis, the correlation was insignificant in multivariate analysis. This indicates that reduced exercise capacity in Group 1 is caused by factors other than infarction size, that is, prolonged bed rest, an enhanced ventilatory response to exercise (VE/VCO 2 slope), and lung congestion (LVEDP) ( Table IV).…”

Determinants of the effects of physical training and of the complications requiring resuscitation during exercise in patients with cardiovascular disease

“…The individual variability regarding the effects of the cardiac rehabilitation programme with exercise therapy is high. Factors to identify the patients who are likely to benefit most from exercise therapy have been studied in sub-populations of cardiac patients [9][10][11][12][13][14][15], but it remains unclear which are the determinants of the improvements in physical exercise performance. Therefore, the present study aimed to identify the determinants of the training effects in cardiac rehabilitation in a large database of patients.…”

“…Because peak exercise capacity and training-induced changes in peak exercise capacity yield prognostic information [6][7][8], the identification of patients who are likely to benefit most from exercise therapy, would be of interest. A number of groups [9][10][11][12][13][14][15] addressed this question in subpopulations of cardiac patients, but it remains unclear which factors determine the changes in physical exercise performance. Up to now, the predictors for the responsiveness to cardiac rehabilitation have not yet been identified on a general cardiac rehabilitation population.…”

O2 Extraction During Exercise Determines Training Effect After Cardiac Rehabilitation in Myocardial Infarction.

“…7,8,14 Hammond et al, 15 van Dixhoorn et al 16 and Heldal et al 17 have reported that the training effect can be predictable from baseline clinical data, baseline fitness, and cardiac status, but they did not evaluate the correlation between an improvement in exercise capacity after ET and hemodynamic or oximetric variables during exercise before ET. In the present study, we measured arteriovenous oxygen content (A-VO2) difference and LV pressure directly during an exercise test at the beginning of ET.…”