Simple and Compelling Biomimetic Metal–Organic Framework Catalyst for the Degradation of Nerve Agent Simulants

Katz, Michael J.; Mondloch, Joseph E.; Totten, Ryan K.; Park, Jin K.; Nguyen, SonBinh T.; Farha, Omar K.; Hupp, Joseph T.

doi:10.1002/ange.201307520

Cited by 126 publications

(90 citation statements)

References 48 publications

(42 reference statements)

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“… and which emphasizes their advantage as protective materials at ambient conditions. Even though other studies have reported the fast hydrolysis of the organophosphate in MOF, it was achieved by a direct contact of MOF with the simulant. In our study, we report the mineralization of DMCP vapors.…”

Section: Resultsmentioning

confidence: 99%

Copper Hydroxyl Nitrate/Graphite Oxide Composite as Superoxidant for the Decomposition/Mineralization of Organophosphate‐Based Chemical Warfare Agent Surrogate

Arcibar‐Orozco

Giannakoudakis

Bandosz

2015

Adv Materials Inter

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or CO 3 − indicating the mineralization of DMCP to form CuCl 2 and CuCO 3 is shown. Even though more DMCP is reactively adsorbed on CuON, its decomposition is faster on CuONGO. Detected NO 2 , which is formed as an intermediate, causes the conversion of an unevaporated DMCP liquid to H 3 PO 4 , as supported by MS results. This mineralization of DMCP happens via an indirect contact with the catalyst. Thus, CuON and CuONGO are considered as highly powerful media for the decontamination of chlorophosphate-based nerve agents.

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Section: Resultsmentioning

confidence: 99%

Copper Hydroxyl Nitrate/Graphite Oxide Composite as Superoxidant for the Decomposition/Mineralization of Organophosphate‐Based Chemical Warfare Agent Surrogate

Arcibar‐Orozco

Giannakoudakis

Bandosz

2015

Adv Materials Inter

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“…NU-1000 and NU-1000-dehyd represent the fastest known phosphoester-containing hydrolysis catalysts so far: 3 times and 30 times faster than found in our previous work with UiO-66 (ref. 10), and 20 times and 200 times faster than the well-known Cr-MIL-101, which contains coordinatively unsaturated Cr III ions linked by benzene dicarboxylates 20 . NU-1000 is also the fastest known MOF-based catalyst for the hydrolysis of GD (Table 1, bottom): 80-fold faster than the MOF HKUST-1 (under similar conditions and 960-fold faster in our buffered solution) which contains Cu II paddlewheel-based nodes and trimesic acid linkers 21 .…”

mentioning

confidence: 97%

“…For example, using the well-known twelve-connected Zr 6 -based MOF UiO-66, we were able to catalytically hydrolyse the nerve agent simulant dimethyl 4-nitrophenyl phosphate (DMNP, see Fig. 2a) 10 . Given their known outstanding thermal 11 , mechanical 12 and hydrolytic stabilities 13 , MOFs containing Zr 6 nodes and multitopic carboxylated linkers are among the most promising classes of potentially catalytic materials for deployment in personal chemical protection.…”

mentioning

confidence: 99%

Destruction of chemical warfare agents using metal–organic frameworks

Mondloch¹,

Katz²,

et al. 2015

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Chemical warfare agents containing phosphonate ester bonds are among the most toxic chemicals known to mankind. Recent global military events, such as the conflict and disarmament in Syria, have brought into focus the need to find effective strategies for the rapid destruction of these banned chemicals. Solutions are needed for immediate personal protection (for example, the filtration and catalytic destruction of airborne versions of agents), bulk destruction of chemical weapon stockpiles, protection (via coating) of clothing, equipment and buildings, and containment of agent spills. Solid heterogeneous materials such as modified activated carbon or metal oxides exhibit many desirable characteristics for the destruction of chemical warfare agents. However, low sorptive capacities, low effective active site loadings, deactivation of the active site, slow degradation kinetics, and/or a lack of tailorability offer significant room for improvement in these materials. Here, we report a carefully chosen metal-organic framework (MOF) material featuring high porosity and exceptional chemical stability that is extraordinarily effective for the degradation of nerve agents and their simulants. Experimental and computational evidence points to Lewis-acidic Zr(IV) ions as the active sites and to their superb accessibility as a defining element of their efficacy.

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“…A very recent publication focuses on the field‐effect chemical sensors using UiO‐66‐NH 2 for nerve agent (alkyl phosphonate, DMMP) detection . The [Zr 6 O 4 (OH) 4 ] 12+ cluster of the UiO‐66 type materials has been of specific interest because of its remarkably high activity toward phosphate ester hydrolysis . Signal transduction was achieved by monitoring the work function shift of UiO‐66‐NH 2 ‐coated electrodes upon exposure to ppb‐level (down to 3 ppb) concentrations of the target simulant.…”

Section: Trace Gas Enrichment and Sensingmentioning

confidence: 99%

Adsorption and Detection of Hazardous Trace Gases by Metal–Organic Frameworks

et al. 2018

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The quest for advanced designer adsorbents for air filtration and monitoring hazardous trace gases has recently been more and more driven by the need to ensure clean air in indoor, outdoor, and industrial environments. How to increase safety with regard to personal protection in the event of hazardous gas exposure is a critical question for an ever-growing population spending most of their lifetime indoors, but is also crucial for the chemical industry in order to protect future generations of employees from potential hazards. Metal-organic frameworks (MOFs) are already quite advanced and promising in terms of capacity and specific affinity to overcome limitations of current adsorbent materials for trace and toxic gas adsorption. Due to their advantageous features (e.g., high specific surface area, catalytic activity, tailorable pore sizes, structural diversity, and range of chemical and physical properties), MOFs offer a high potential as adsorbents for air filtration and monitoring of hazardous trace gases. Three advanced topics are considered here, in applying MOFs for selective adsorption: (i) toxic gas adsorption toward filtration for respiratory protection as well as indoor and cabin air, (ii) enrichment of hazardous gases using MOFs, and (iii) MOFs as sensors for toxic trace gases and explosives.

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Simple and Compelling Biomimetic Metal–Organic Framework Catalyst for the Degradation of Nerve Agent Simulants

Cited by 126 publications

References 48 publications

Copper Hydroxyl Nitrate/Graphite Oxide Composite as Superoxidant for the Decomposition/Mineralization of Organophosphate‐Based Chemical Warfare Agent Surrogate

Copper Hydroxyl Nitrate/Graphite Oxide Composite as Superoxidant for the Decomposition/Mineralization of Organophosphate‐Based Chemical Warfare Agent Surrogate

Destruction of chemical warfare agents using metal–organic frameworks

Adsorption and Detection of Hazardous Trace Gases by Metal–Organic Frameworks

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