Silver nanoparticles as potential antiviral agents against African swine fever virus

Dung, Trần Thị Ngọc; Nam, Vu Nang; Nhan, Tran Thi; Ngoc, Trinh Thi Bich; Minh, Luu Quang; Nga, Bui Thi To; Le, Van Phan; Quang, Đặng Viết

doi:10.1088/2053-1591/ab6ad8

Cited by 72 publications

(32 citation statements)

References 62 publications

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“…Ag NPs have been shown to have a high antiviral capability toward the African swine fever virus, through interacting with its protein shell, and thereby preventing viral penetrating into the animal’s cell [ 105 ]. One study, involving Ag 2 S NPs, indicated that the antiviral capacity predominantly influences the stages of viral RNA replication and budding [ 106 ].…”

Section: Antimicrobial Mechanismsmentioning

confidence: 99%

Antimicrobial Properties of the Ag, Cu Nanoparticle System

Fan

Yahia

Sacher

2021

Biology

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Microbes, including bacteria and fungi, easily form stable biofilms on many surfaces. Such biofilms have high resistance to antibiotics, and cause nosocomial and postoperative infections. The antimicrobial and antiviral behaviors of Ag and Cu nanoparticles (NPs) are well known, and possible mechanisms for their actions, such as released ions, reactive oxygen species (ROS), contact killing, the immunostimulatory effect, and others have been proposed. Ag and Cu NPs, and their derivative NPs, have different antimicrobial capacities and cytotoxicities. Factors, such as size, shape and surface treatment, influence their antimicrobial activities. The biomedical application of antimicrobial Ag and Cu NPs involves coating onto substrates, including textiles, polymers, ceramics, and metals. Because Ag and Cu are immiscible, synthetic AgCu nanoalloys have different microstructures, which impact their antimicrobial effects. When mixed, the combination of Ag and Cu NPs act synergistically, offering substantially enhanced antimicrobial behavior. However, when alloyed in Ag–Cu NPs, the antimicrobial behavior is even more enhanced. The reason for this enhancement is unclear. Here, we discuss these results and the possible behavior mechanisms that underlie them.

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Section: Antimicrobial Mechanismsmentioning

confidence: 99%

Antimicrobial Properties of the Ag, Cu Nanoparticle System

Fan

Yahia

Sacher

2021

Biology

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“…Their study demonstrates a significant drop in viral contamination after spraying of Ag NPs. 329 Sharma et al produced Ag NPs from medicinal plants ( Andrographis paniculata , Phyllanthus niruri , and Tinospora cordifolia ) via a green method and evaluated their antiviral properties against chikungunya virus. 289 The 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) essay results reveal that Ag NPs synthesized from A. paniculata showed the maximum inhibition of virus activity.…”

Section: Antibacterial and Antiviral Properties Of Nanomaterialsmentioning

confidence: 99%

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Balasubramaniam

Prateek

Ranjan

et al. 2020

ACS Pharmacol. Transl. Sci.

199

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The ongoing worldwide pandemic due to COVID-19 has created awareness toward ensuring best practices to avoid the spread of microorganisms. In this regard, the research on creating a surface which destroys or inhibits the adherence of microbial/viral entities has gained renewed interest. Although many research reports are available on the antibacterial materials or coatings, there is a relatively small amount of data available on the use of antiviral materials. However, with more research geared toward this area, new information is being added to the literature every day. The combination of antibacterial and antiviral chemical entities represents a potentially path-breaking intervention to mitigate the spread of disease-causing agents. In this review, we have surveyed antibacterial and antiviral materials of various classes such as small-molecule organics, synthetic and biodegradable polymers, silver, TiO2, and copper-derived chemicals. The surface protection mechanisms of the materials against the pathogen colonies are discussed in detail, which highlights the key differences that could determine the parameters that would govern the future development of advanced antibacterial and antiviral materials and surfaces.

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“…Nanoparticles (NPs) are one of the excellent findings of nanotechnology to solve the day to day issues of the current world. One of the most important metallic NPs is silver nanoparticles (AgNPs); because of their chemical stability, good conductivity, antibacterial, antiviral, antifungal and cytotoxic activities 3 – 5 .…”

Section: Introductionmentioning

confidence: 99%

Polyphenols profile of pomegranate leaves and their role in green synthesis of silver nanoparticles

Swilam

Nematallah

2020

Sci Rep

113

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The current study reports on polyphenols profile of pomegranate leaves (PL) Punica granatum grown in Egypt and exhibiting their role in development of an eco-friendly method of green synthesis of silver nanoparticles (AgNPs). PL aqueous alcohol extract was fractionated, the major phenolic compound was isolated from the polyphenols rich fraction (ethyl acetate fraction) and identified by conventional and spectroscopic methods of analysis as ellagic acid. Furthermore, the fraction was standardized and analysed using UPLC-PDA-UV and LC–MS-MS techniques revealing tentative identification of 23 polyphenolic compounds, quantifying ellagic acid as 43.14 ± 0.57 μg/mg of the fraction. AgNPs were successfully synthesized with the aid of polyphenols rich fraction. This is the first report revealing the systematic optimization of the green synthesis process using various independent variables. AgNPs were characterized by adopting UV–Vis spectroscopy, FTIR, XRD, and SEM, which revealed strong SPR band within average of λ max 425 nm and polygonal shaped nanoparticles of 26.22 nm size, respectively. The antimicrobial efficacies of AgNPs and polyphenols rich fraction were tested against Gram-positive bacteria (Bacillus subtilis, Staphylococcus aureus, and Sarcina lutea), Gram-negative bacteria (Salmonella paratyphi, Escherichia coli, and Pseudomonas aeruginosa) and fungi (Candida albicans). AgNPs showed a concentration-dependent activity against all the tested microorganisms.

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Silver nanoparticles as potential antiviral agents against African swine fever virus

Cited by 72 publications

References 62 publications

Antimicrobial Properties of the Ag, Cu Nanoparticle System

Antimicrobial Properties of the Ag, Cu Nanoparticle System

Antibacterial and Antiviral Functional Materials: Chemistry and Biological Activity toward Tackling COVID-19-like Pandemics

Polyphenols profile of pomegranate leaves and their role in green synthesis of silver nanoparticles

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