Silver-decorated black phosphorus: a synergistic antibacterial strategy

Abstract

Black phosphorus (BP) exhibits great potential as antibacterial materials due to its unique photocatalytic activity. However, the unsatisfactory optical absorption and quick recombination of photoinduced electron–hole pairs restrain its photocatalytic antibacterial performance. In this work, silver nanoparticles (AgNPs) were decorated on BP to construct BP@AgNPs nanohybrids and then introduced into polymer scaffold. On one hand, AgNPs with broad optical absorption range could improve the light absorption ability of BP, thus promoting the generation of photoinduced electron-hole pairs. On the other hand, the AgNPs simultaneously serve as excellent electron acceptors, which were able to suppress the repaid recombination of electron-holes pairs by accelerating the photoexcited electron transition. Fluorescence probe experiment verified that BP@AgNPs promoted the generation of reactive oxygen species, which could disrupt bacteria membrane, damage DNA and oxide proteins, and finally lead to bacteria apoptosis. As a result, the scaffold possessed strong antibacterial efficiency with a bactericidal rate of 97% under light irradiation. Moreover, the scaffold also exhibited good cytocompatibility. This work highlighted a new strategy to develop photocatalytic antibacterial scaffold for bone implant application.

In Situ Growth of a Metal–Organic Framework on Graphene Oxide for the Chemo-Photothermal Therapy of Bacterial Infection in Bone Repair

“…In the case of the PLLA/GO scaffold, two peaks at 1743 and 3453 cm –1 were detected in the spectra, which were assigned to the stretching vibration of CO belonging to PLLA and the hydroxyl group, respectively . In the case of the PLLA/ZIF@GO scaffold, the hydroxyl group and CO peak were redshifted, indicating hydrogen bonding between ZIF@GO and PLLA …”

“…43 In the case of the PLLA/ ZIF@GO scaffold, the hydroxyl group and CO peak were redshifted, indicating hydrogen bonding between ZIF@GO and PLLA. 44 In general, the oxygenated functional group of the GO nanosheets possessed high surface activity, which made it difficult to form good interface bonds with PLLA with low polarity. Overall, these results indicated that the ZIF-8@GO nanosystem effectively alleviated the agglomeration of GO in the PLLA matrix.…”

Construction of magnetic nanochains to achieve magnetic energy coupling in scaffold

“…The cytocompatibility of scaffolds is a necessary and crucial element in the bone repair process because it determines whether cells can adhere, grow, and proliferate on the scaffold [ 36 , 37 ]. Herein, the cytocompatibility of the PLLA, PLLA/Fe 3 O 4 and PLLA/Fe 3 O 4 @SiO 2 scaffolds were assessed.…”

Stress-Induced Dual-Phase Structure to Accelerate Degradation of the Fe Implant

“…The cells cultured on all extracts showed obvious proliferation with the increase of culture time, which was consistent with the CCK-8 results. Moreover, the cells remained healthy and showed a clear trend of expansion, indicating that the degradation products had little effect on cell growth and metabolic activities. − To sum up, both CCK-8 assay and fluorescence staining results demonstrated good biocompatibility of the Fe30Mn6Si alloy. The higher cell viability attributed to the release of Si 4+ in the degradation process was beneficial to osteoblasts’ proliferation and differentiation .…”