Silver-109/Silver/Gold Nanoparticle-Enhanced Target Surface-Assisted Laser Desorption/Ionisation Mass Spectrometry—The New Methods for an Assessment of Mycotoxin Concentration on Building Materials

Abstract

This study aimed to detect and quantify mycotoxins on building materials using innovative laser mass spectroscopy methods—silver-109/silver/gold nanoparticle-enhanced target surface-assisted laser desorption/ionisation mass spectrometry (109AgNPs, AgNPs and AuNPs SALDI). Results from SALDI-type methods were also compared with commonly used matrix-assisted laser desorption/ionization (MALDI) mass spectrometry. Standards of seven moulds mycotoxin in a final concentration of 100 µg/mL for patulin, citrinin, 3-nitropropionic acid, alternariol and 20 µg/mL for sterigmatocystin, cyclopiazonic acid, roquefortine C in the mixture were tested in pure solutions and after extraction from the plasterboards. Among the studied SALDI-type method, the lowest detection limits and the highest signal intensity of the mycotoxins tested were obtained with the use of 109AgNPs SALDI MS. The 109AgNPs method may be considered as an alternative to the currently most frequently used method MALDI MS and also liquid chromatography tandem mass spectrometry LC-MS/MS for mycotoxin determination. Future studies should attempt to use these methods for mass spectrometry imaging (MSI) to evaluate spatial distribution and depth of mycotoxin penetration into building materials.

Carbon-Based Nanoparticles and Their Surface-Modified Counterparts as MALDI Matrices

“…Metal-based nanoparticles have a high ionization efficiency and chemical stability, similar to carbon-based nanoparticles. The production cost of metallic nanoparticles is, however, generally lower than that of carbon-based nanoparticles, a property that has contributed to their extensive use as MALDI matrices. − …”

Infrared pulsed fiber laser‐produced silver‐109‐nanoparticles for laser desorption/ionization mass spectrometry of amino acids

“…Monoisotopic silver‐109 nanoparticles ( 109 AgNPs) were found to be very efficient for cationization of various type of compounds, for example, amino acids, fatty acids, saccharides, or mould toxins 11–14 . In this article, we present quantification result of amino acids on steel plate covered with chemically pure silver‐109 nanoparticles produced by a new method with the use of 1064‐nm pulsed fiber laser with 2D galvanometer scanner.…”

“…[7][8][9][10] Monoisotopic silver-109 nanoparticles ( 109 AgNPs) were found to be very efficient for cationization of various type of compounds, for example, amino acids, fatty acids, saccharides, or mould toxins. [11][12][13][14] In this article, we present quantification result of amino acids on steel plate covered with chemically pure silver-109 nanoparticles produced by a new method with the use of 1064-nm pulsed fiber laser with 2D galvanometer scanner. We also compare manual laser desorption/ ionization mass spectrometry (LDI MS) and semiautomatic laser desorption/ionization mass spectrometry imaging (LDI MSI) in quantification of amino acids along with discussion of results and comparison with various surface-assisted laser desorption ionization (SALDI) and MALDI methods previously used in amino acids analysis.…”

Strong Coupling in a Hybrid System of Silver Nanoparticles and J-Aggregates at Room Temperature

“…Second, the optical response of metal nanoparticles can be easily controlled by adjusting the shape, size, and chemical composition of the particles, which makes the construction of metamaterials possible. Silver and gold nanoparticles − are often the most frequently used and best choice in the field of plasmonic materials.…”