Abstract:Enzymatic reactions are often terminated by severe aqueous environments. Inspired by bio‐protection of silk cocoons, a system of silk fibroin (SF) nanococoons is developed, which is capable of providing a bio‐protective environment for enzymatic activities on one hand, and facilitating the process of cascade enzymatic reactions on the other hand. This gives rise to the significant enhancement in enzymatic stability and efficacy. For instance, the protected glucose oxidase and horseradish peroxidase enzymes exh… Show more
“…However, when the content of a-helical structure is higher, silk protein materials exhibit better elasticity. 57 Its secondary structure plays a crucial role in determining its properties. Controllable optimization of various properties of silk proteins can be achieved by precisely regulating the secondary structure of silk proteins, especially by rationally adjusting the ratio of crystalline and non-crystalline regions.…”
Section: Formation Process and Structural Characteristics Of Natural ...mentioning
This review summarizes the hierarchical structure and multifaceted properties of natural silk fibers, and provides an in-depth analysis of their extensive applications in the realms of biomedicine and advanced smart fiber technology.
“…However, when the content of a-helical structure is higher, silk protein materials exhibit better elasticity. 57 Its secondary structure plays a crucial role in determining its properties. Controllable optimization of various properties of silk proteins can be achieved by precisely regulating the secondary structure of silk proteins, especially by rationally adjusting the ratio of crystalline and non-crystalline regions.…”
Section: Formation Process and Structural Characteristics Of Natural ...mentioning
This review summarizes the hierarchical structure and multifaceted properties of natural silk fibers, and provides an in-depth analysis of their extensive applications in the realms of biomedicine and advanced smart fiber technology.
“…[87][88][89][90][91][92][93][94][95][96][97][98][99][100][101] Recently, various works have been published addressing the use of silk biomaterials as excellent supports for the covalent and noncovalent immobilization of enzymes with high retention of catalytic activity and stability against various stresses (Table 3). [100][101][102][103][104][105][106][107][108][109][110][111][112][113][114] Silk nanofiber (SNF) is an excellent candidate for enzyme immobilization due to superior stiffness, larger specific surface area, higher interconnectivity and porosity with high capacity for loading enzymes. In this regard, Lee et al 91 prepared SF nanofibers by electrospinning and applied it for immobilization of α-CT.…”
Section: Silk Fibroin-based Supports (Carriers) For Enzyme Immobiliza...mentioning
The unique catalytic properties of enzymes are greatly recognised and led to effective utilisation in the production of useful medicinal intermediates, food industry, and biofuels from sustainable sources. However, the...
“…An innovative system of silk fibroin nanococoons is developed on the basis of bioprotection of silk cocoons. [ 145 ] Enzymatic activity is enabled by a bioprotective environment on one hand, and cascade enzymatic reactions are facilitated on the other hand.…”
Section: Stimuli‐responsive Nanocomposite Hydrogels and Application M...mentioning
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