Silicone rubber-hydrogel composites as polymeric biomaterials

Cífková, I.; Lopour, P.; Vondráček, Petr; Jelínek, Filip

doi:10.1016/0142-9612(90)90093-6

Cited by 51 publications

(23 citation statements)

References 6 publications

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“…As can be seen from the figure, the swelling of PVP/ PDMS-IPNs in water increases linearly with increasing concentration of PVP in the PVP/PDMS-IPNs. Because PVP is a hydrogel, 15,21 it is natural that the IPNs swell in proportion to their PVP content.…”

Section: Swelling In Watermentioning

confidence: 99%

Transparency and wettability of PVP/PDMS‐IPN synthesized in different organic solvents

Hillerström

Andersson²,

Pedersen

et al. 2009

J of Applied Polymer Sci

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An interpenetrating polymer network (IPN) combining a hydrophobic polymer (polydimethylsiloxane, PDMS) and a hydrophilic polymer (polyvinylpyrrolidone, PVP) was synthesized in different solvents via a two-step preparation method. The solvent used during polymerization of the IPN showed a significant impact on the properties of the PVP/PDMS-IPN. The choice of solvent was affecting both the wettability and transparency of the PVP/ PDMS-IPN. The PVP/PDMS-IPNs turned hydrophilic in all the solvents used in this study, but the transition from a hydrophobic to a hydrophilic PVP/PDMS-IPN occurred at lower PVP concentration if a solvent with similar solubility parameter as PVP was chosen. Also, the PVP/PDMS-IPNs were transparent when the samples were polymerized in a good solvent for PVP. It was concluded that the properties of the PVP/PDMS-IPN can be tuned by the selection of the solvent used during polymerization. The size of the PVP phase domains in the PVP/PDMS-IPNs were analyzed with X-ray scattering techniques (SAXS), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and differential scanning calorimetry (DSC), and the sizes of the domains were found to be smaller than 350 nm.

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Section: Swelling In Watermentioning

confidence: 99%

Transparency and wettability of PVP/PDMS‐IPN synthesized in different organic solvents

Hillerström

Andersson²,

Pedersen

et al. 2009

J of Applied Polymer Sci

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“…The challenge lies in not impairing their oxygen permeability and optical transparency. Such combinations can be achieved by the copolymerization of methacrylate‐functionalized siloxane macromers and hydrophilic comonomers, such as 2‐hydroxyethyl methacrylate, N,N ‐dimethylacrylamide (DMA), and N ‐vinyl pyrrolidone . The copolymerization method has been applied extensively for the preparation of contact lenses …”

Section: Introductionmentioning

confidence: 99%

Radical/Addition polymerization silicone hydrogels with simultaneous interpenetrating hydrophilic/hydrophobic networks

Yang

Zhang

et al. 2014

J of Applied Polymer Sci

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Transparent silicone hydrogels with interpenetrating hydrophilic/hydrophobic networks were simultaneously synthesized on the basis of the radical polymerization of the methacrylic monomer of 3‐methacryloxypropyl tris(trimethylsiloxy) silane (TRIS)/N,N‐dimethylacrylamide (DMA) and the addition polymerization of hydroxyl‐grafted polysiloxane (HPSO)/isophorone diisocyanate. The curing temperature was set at 80°C by a differential scanning calorimetry study. The polymerization process was studied by in situ Fourier transform infrared spectroscopy. The results indicate that the curing time was about 4.5 min, and the addition polymerization had a faster rate than radical polymerization. Then, the radical polymerization rate increased rapidly, and this led to instant curing. The interpenetrating polymer network (IPN) silicone hydrogels were characterized by swelling kinetics and dynamic mechanical thermal analysis. The results show that all of the hydrogels reached swelling equilibrium at about 4 h in water, and the IPN silicone hydrogels with a hydrophobic network of HPSO indicated a slower water transport than that of the copolymerization hydrogel of DMA and TRIS. The hydrophobic network was finely dispersed in the hydrophilic network, and the increasing hydrophobic network of HPSO decreased the glass‐transition temperature of the IPN silicone hydrogels. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2015, 132, 41399.

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“…For the fabrication of actuators, several types of hydrogels have been tested and evaluated . For biomedical applications composite materials combining the good mechanical properties and non‐toxicity of silicone rubber with the excellent biocompatibility of such swelling hydrogels have been tested . For example, a combination of a polypyrrole matrix and a polyol‐borate network is able to generate contractile stress up to 27 MPa and to lift objects 380 times heavier than itself .…”

Section: Introductionmentioning

confidence: 99%

Self‐bending hydrogel actuation for electrode shafts in cochlear implants

Stieghorst

Tegtmeier

Aliuos

et al. 2014

Physica Status Solidi (a)

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A self‐bending electrode shaft for application in cochlear implants (CI) is presented. It is desired to reduce the distance between the electrode contacts and nerve cells in the modiolus of the inner ear. Therefore a coextrusion and overmolding device to fabricate a novel electrode shaft consisting of an eccentrically positioned hydrogel swelling actuator was established. Finite‐element‐analysis (FEA) was performed to analyse the self‐bending effect in relationship to the applied hydrostatic pressure. The mechanical actuation of a fabricated electrode shaft was tested in vitro by injection of water into the hydrogel. Curving of the electrode shaft was observed. Osmotic pressure in relation to the mass fraction of the swelling polymer inside the hydrogel was calculated.

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Silicone rubber-hydrogel composites as polymeric biomaterials

Cited by 51 publications

References 6 publications

Transparency and wettability of PVP/PDMS‐IPN synthesized in different organic solvents

Transparency and wettability of PVP/PDMS‐IPN synthesized in different organic solvents

Radical/Addition polymerization silicone hydrogels with simultaneous interpenetrating hydrophilic/hydrophobic networks

Self‐bending hydrogel actuation for electrode shafts in cochlear implants

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